No registrations found.
ID
Source
Brief title
Health condition
Cohort follow-up study.
Sponsors and support
Intervention
Outcome measures
Primary outcome
Thromboembolic disease during three months follow-up in all patients.
Secondary outcome
N/A
Background summary
3503 eligible patients of whom 197 excluded (5%);
VTE complications during follow-up in patients with initial normal tests:
1. in patients with CDR indicating PE unlikely and normal D-dimer 0.5 %;
2. in patients with normal helical CT: 1.3 %.
Study objective
It is safe to withhold anticoagulant treatment in patients with clinically suspected PE who have either a combination of CDR indicating PE unlikely and normal D-dimer test or CDR indicating PE likely or abnormal D-dimer test and normal helical CT.
Study design
N/A
Intervention
Diagnosis of PE by CDR, D-dimer and helical CT.
Department of Thrombosis and Haemostasis<br>
Room C4-68<br>
P.O Box 9600
M.V. Huisman
Albinusdreef 2
Leiden 2300 RC
The Netherlands
+31 (0)71 5262085
m.v.huisman@lumc.nl
Department of Thrombosis and Haemostasis<br>
Room C4-68<br>
P.O Box 9600
M.V. Huisman
Albinusdreef 2
Leiden 2300 RC
The Netherlands
+31 (0)71 5262085
m.v.huisman@lumc.nl
Inclusion criteria
Adult patients more than 18 years old with clinically suspected pulmonary embolism.
Exclusion criteria
1. Pregnancy;
2. Allergy to contrast media;
3. No geographic possibility to return for follow-up;
4. Treatment with therapeutic heparin for more than 24 hours;
5. Indication for thrombolytic therapy.
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| NTR-new | NL537 |
| NTR-old | NTR581 |
| Other | : N/A |
| ISRCTN | ISRCTN56430379 |
Summary results
<br><br>
2. Thromb Haemost. 2007 Jun;97(6):944-8.<br>