No registrations found.
ID
Source
Health condition
posttraumatic stress, substance use disorder, alcohol dependence, substance use dependence, trauma, seeking safety
Sponsors and support
Postbus 154
7400 AD Deventer
the Netherlands
NISPA
Postbus 9104
6500 HE Nijmegen
Intervention
Outcome measures
Primary outcome
Severity of substance use as measured with the EuropASI at the start of treatment, the end of treatment and follow-up after three months.
Secondary outcome
Traumatic symptoms, as measured with the Self-report Inventory for PTSD at the start of treatment, the end of treatment and follow-up after three months.
Background summary
A randomized controlled trial in outpatient substance use patients and a controlled trial in an inpatient SUD population, to test the efficacy of Seeking Safety in addition to TAU, compared to TAU. It is expected that the intervention group will improve more on substance use severity and trauma symptoms (as measured with the EuropASI and the SRIP) than the control group.
Study objective
Intervention group will show more improvement on substance use and trauma-related symptoms than control group.
Study design
Start of treatment, end of treatment (three months after start) and three months after end of treatment.
Intervention
Seeking Safety. A cognitive behavioral therapy focused on integrated treatment of substance use and PTSD, through coping-skillstraining, psycho-education and learning to obtain safety in all areas of life. It consists of 25 sessions of 75 minutes which will be offered twice a week for a duration of three months. This treatment will be offered in addition to treatment as usual, which is cognitive behavioral based relapse prevention. This treatment consists of weekly sessions of 2 hours for three months. The control group will only receive TAU.
Inclusion criteria
1. Patient is indicated for clinical, day time or outpatient treatment within Tactus Addiction Treatment during the research period;
2. Age 18 years or older;
3. Speaks and understands Dutch language;
4. Signed informed consent;
5. Criterium A of PTSD and a score of ¡Ý 29 on the SRIP.
Exclusion criteria
1. Severe psychiatric disorders that impede participation such as a severe bipolar or psychotic disorder;
2. Severe (self) destructive behavior;
3. Insufficient level of intelligence to participate in the study (estimated IQ below 85);
4. Active PTSD treatment within the last six months.
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| NTR-new | NL2938 |
| NTR-old | NTR3084 |
| Other | METC Twente : 33469 |
| ISRCTN | ISRCTN wordt niet meer aangevraagd. |