No registrations found.
ID
Source
Brief title
Health condition
Raynaud's phenomenon
Sponsors and support
Intervention
Outcome measures
Primary outcome
The primary objective of the study is to determine the sensitivity and specificity of NCM in combination with ANA for predicting an underlying CTD in children with Raynaud's.
Secondary outcome
- To study the changes of the nailfold capillaroscopic pattern over time (>5 years): pattern, number of capillaries, number of giant capillaries, hemorrhages
- To describe the characteristics of our cohort of children/young adults with Raynaud’s phenomenon with a follow-up of >5 years
- To study the predictive value of symptoms specific for CTD and abnormal lab tests (CRP, BSE, kidney function, complement C3 and C4, erythrocyteuria, cryoglobulinemia)
Background summary
The CARY study is a retrospective cohort study to determine the predictive value of NCM and ANA in children with Raynaud's phenomenon.
Study objective
The hypothesis is that especially the combination of nailfold capillary microscopy (NCM) and antinuclear antibodies (ANA) will be of good predictive value in children with Raynaud's.
Study design
Baseline: retrospective data from between 2008 and 2013
Follow-up: one visit in 2019
Intervention
None
Inclusion criteria
- Diagnoses of Raynaud's phenomenon
- Underwent NCM when they were under 18 years of age
- Currently 16 years of age or older
Exclusion criteria
None
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| NTR-new | NL7314 |
| NTR-old | NTR7530 |
| Other | ABR-number : 67776 |