No registrations found.
ID
Source
Brief title
Health condition
diabetic retinopathy (DR)
Sponsors and support
Intervention
Outcome measures
Primary outcome
treatment success
Secondary outcome
1 year BCVA and macular thickness
Background summary
We aim to evaluate hyperreflective dots (HRDs) on optical coherence tomography (OCT) in patients with diabetic macular edema (DME) to assess
their relationship with the treatment outcomes.
Study objective
The number of pretreatment HRDs on OCT can predict response to intravitreal anti-VEGF therapy in DME.
Study design
baseline, 1 year
Intervention
none
Inclusion criteria
DME patients with completion of 6 intravitreal injections of anti‑VEGF at UMCG and at least 1 year follow‑up with BCVA
and OCT after start of the treatment will be included.
Exclusion criteria
high myopia (>6 diopters), glaucoma, media opacities interfering with OCT imaging,
combined retinal disease, intraocular surgery within 12 weeks prior to the first injection,
vitreomacular traction on SD‑OCT and those whose SD‑OCT images were of poor quality
Design
Recruitment
IPD sharing statement
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| NTR-new | NL8392 |
| Other | METC UMCG : METc2019/599 |