No registrations found.
ID
Source
Brief title
Health condition
1. PGD-AS;
2. preimplantation diagnosis;
3. infertility;
4. bad implantation.
Sponsors and support
Laarbeeklaan 101
1090 Jette
Laarbeeklaan 101
1090 Jette
Intervention
Outcome measures
Primary outcome
Pregnancy rates in both groups.
Secondary outcome
Implantation rate.
Background summary
Two hundred patients who attended the Fertility Clinic of a University Hospital and who underwent three or more IVF or ICSI attempts were recruited and randomized into two groups. Embryos of patients enrolled into one arm of the study were subjected to genetic analysis of the embryos at day three of embryonic development. In the control group, no preimplantation genetic analysis was performed. Two embryos were transferred in both groups on day five.
Study objective
With this study, we test the hypothesis that preimplantation diagnosis for aneuploidy screening improves the implantation and pregnancy rates in patients with recurrent failed IVF/ICSI attempts.
Study design
N/A
Intervention
ICSI in both groups, PGD-AS in the study group.
Centre for Reproductive Medicine
Christophe Blockeel
Laarbeeklaan 101
Brussels 1090
Belgium
cblockee@uzbrussel.be
Centre for Reproductive Medicine
Christophe Blockeel
Laarbeeklaan 101
Brussels 1090
Belgium
cblockee@uzbrussel.be
Inclusion criteria
1. Three or more than three failed IVF-ICSI attempts;
2. age <37 years old.
Exclusion criteria
Less than three IVF -ICSI attempts.
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| NTR-new | NL1103 |
| NTR-old | NTR1138 |
| Other | : N/A |
| ISRCTN | ISRCTN wordt niet meer aangevraagd. |