No registrations found.
ID
Source
Brief title
Health condition
Fat graft
Lipofilling
Autologous fat transplantation
Volumetric outcome
Predictors
Patient satisfaction
Vet transplantatie
Lipofilling
Volumetische uitkomst
Voorspellers
Patient tevredenheid
Sponsors and support
Intervention
Outcome measures
Primary outcome
Volumetric differences between baseline and 1 year after fat grafting measured by 3d stereophotogrammetry
Secondary outcome
Patient satisfaction measured by FACE-Q questionnaire
Background summary
Autologous fat grafts are commonly used in reconstructive and aesthetic surgery. The retention of the transplanted fat is 20-90%. The predictors of this volume retention remain unclear. This study aims to relate patient’s bodyweight, smoking habits, estradiol level and the post-menopausal status to the volumetric outcome and satisfaction of patients after facial fat grafting. The design of the study is a prospective observational cohort study with invasive measurements.
All patients who will undergo a facial fat graft procedure at the department of Oral and Maxillofacial Surgery at the University Medical Center Groningen (the Netherlands) will be included.
Volumetric outcome will be measured by 3D stereophotogrammetry at 6 weeks, 6 months, and 12 months. Patient satisfaction will be evaluated by the FACE-Q questionnaire. 17b oestradiol and AMH measurements will be generalized using a blood sample.
Burden risk of participation the study thought to be very low.
Study objective
Autologous fat grafts are commonly used in reconstructive and aesthetic surgery. The retention of the transplanted fat is 20-90%. The predictors of this volume retention remain unclear. This study aims to relate patient’s bodyweight, smoking habits, estradiol level and the post-menopausal status to the volumetric outcome and satisfaction of patients after facial fat grafting.
The hypothesis is that smoking and low estradiol levels will influence the volumetric outcome negatively.
Study design
Preoperative (4-6 weeks preoperatively)
1 week postoperatively
6 weeks postoperatively
6 months postoperatively
12 months postoperatively
Intervention
Facial fat grafting
A.J. Tuin
Hanzeplein 1
Groningen 9713GZ
The Netherlands
(0031) 050-3613846
a.j.tuin@umcg.nl
A.J. Tuin
Hanzeplein 1
Groningen 9713GZ
The Netherlands
(0031) 050-3613846
a.j.tuin@umcg.nl
Inclusion criteria
Women
Age between 18 and 75 years
Facial fat graft procedure at the department of Oral
Maxillofacial surgery in the University Medical Center Groningen
Exclusion criteria
Children (under 18 years)
Men
Patients older than 75 years
Pregnancy at the moment of the fat graft procedure
Contraindications for fat grafting: ASA class 3 or 4, coagulation disorders, body dismorphic disorder, use of anticoagulantia what can not be stopped for this procedure, medication with interference with cytochroom P450, 3A4 or 1A2
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| NTR-new | NL5177 |
| NTR-old | NTR5325 |
| Other | METc UMCG : METc 2014/500 |