No registrations found.
ID
Source
Brief title
Sponsors and support
Intervention
Outcome measures
Primary outcome
Respiratory system mechanics (compliance and resistance).
Secondary outcome
Arterial pCO2.
Background summary
N/A
Study objective
First, mechanical ventilation with a gas mixture composed of helium and oxygen is only beneficial in patients with obstructive RSV LRTD. Hence correct identification of the clinical phenotype is necessitated. This can be done with lung function testing, including compliance and resistance.
Second, the beneficial effect of heliox can be detected with repeated EIT measurements.
Intervention
Mechanical ventilation with heliox.
P.O. Box 7057
M.C.J. Kneyber
Amsterdam 1007 MB
The Netherlands
+31 (0)20 4442413
m.kneyber@vumc.nl
P.O. Box 7057
M.C.J. Kneyber
Amsterdam 1007 MB
The Netherlands
+31 (0)20 4442413
m.kneyber@vumc.nl
Inclusion criteria
Mechanically ventilated infants younger than 12 months of age with a virologically proven RSV infection.
Exclusion criteria
Older than 12 months of age, no informed consent, prior use of corticosteroids, infants on high-frequency oscillatory ventilation and infant wit a haemodynamically significant congenital heart defect.
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| NTR-new | NL198 |
| NTR-old | NTR235 |
| Other | : N/A |
| ISRCTN | ISRCTN98152468 |