No registrations found.
ID
Source
Brief title
Health condition
Increased lung density, decreased amount of air in the lung, verhoogde longdichtheid, verminderde luchthoudendheid van de long.
Sponsors and support
Intervention
Outcome measures
Primary outcome
Lung aeration of the 12 lung regions evaluated through Lung Ultrasound (LUS).
Secondary outcome
- Estimation of lung aeration on CT scans
- Estimation of lung aeration by a conventional visual LUS scoring
- Other LUS findings (e.g., pleural line abnormalities, lung pulse, lung sliding abolition, pleural effusion)
Background summary
Monitoring of lung aeration is crucial in Intensive Care Unit (ICU) patients, especially in invasively ventilated patients. The gold standard for measuring lung aeration is chest Computed Tomography (CT). Unfortunately, a chest CT scan is difficult to obtain in invasively ventilated ICU patients and cannot be repeated frequently. Lung Ultrasound (LUS) as a point–of–care imaging tool is increasingly used in the (ICU) setting. Lung aeration by LUS is presently evaluated through semi–quantitative visual scores. Automated quantification could improve accuracy of lung aeration estimations. Our objective is to develop a computer–based algorithm for quantitative LUS analysis that accurately estimates lung aeration. A chest Computed Tomography (CT) scan will be used as the reference test.
Study objective
Artifacts on LUS images adequately reflect chest CT scan findings in invasively ventilated ICU patients; artifacts could be used in a computer–based quantitative algorithm for lung aeration.
Study design
The Lung Ultrasound is performed close in time to the chest CT-scan.
Intervention
Lung Ultrasound
Marcus J. Schultz
Amsterdam 1105 AZ
The Netherlands
+31 (0)20 5662509
m.j.schultz@amc.uva.nl
Marcus J. Schultz
Amsterdam 1105 AZ
The Netherlands
+31 (0)20 5662509
m.j.schultz@amc.uva.nl
Inclusion criteria
- Admitted to the intensive care unit for adults of the Academic Medical Center in Amsterdam, The Netherlands
- Receiving invasive ventilation
- Receiving a chest Computed Tomography (CT) scan on a clinical indication
Exclusion criteria
- Age < 18 years
- Lung Ultrasound (LUS) not feasible (e.g., severe chest trauma, extensive burns, open wounds)
- No written informed consent of the patient or his/her formal representative
- Reported allergy to skin tape, necessary to attach the skin markers to identify fields at chest CT scans
Design
Recruitment
IPD sharing statement
Followed up by the following (possibly more current) registration
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| NTR-new | NL6915 |
| NTR-old | NTR7110 |
| CCMO | NL64089.018.17 |
| OMON | NL-OMON46372 |