No registrations found.
ID
Source
Health condition
sciatica
Sponsors and support
Intervention
Outcome measures
Primary outcome
1. Roland Disability Questionaire
2. Visual Analogue Scale (VAS) for back pain
3. Visual Analogue Scale (VAS) for leg pain
4. Global Perceived effect
Secondary outcome
1. satisfaction
2. use of medication
3. absenteism from work (yes- no)
4. number of operations
Background summary
Sciatica is a common condition afflicting 5-8 /1000 in the general population.
During the first weeks after onset the focus is on adequate pain reduction by use of pain medication or epidural injections with steroids.
The best treatment strategy is not known. Should all patients be injected? Or a subgroup? Or should patients be treated with medication only. What's the effect of different interventions?
To answer this question we compare 3 treatment groups of patients with acute sciatica:
1. pain medication only
2. epidural injection of steroids and local aneshetic
3. epidural injections of local anesthetic only
These are followed during 6 months. Outcomes are measured and compared using various scales including the Roland Morris scale and VAS.
In addition the costs are measured in terms of absenteism from work and number of operations (secondary outcome measures)
Study objective
Epidural administration of corticosteroids in early onset sciatica gives clinically relevant pain reduction and functional recovery.
Study design
0-3-6 weeks, 3-6 months
Intervention
three groups:
1. pain medication only
2. epidural injection of steroids and local aneshetic
3. epidural injections of local anesthetic only
B. Meulen, ter
Amsterdam 1064 AE
The Netherlands
020-5108911 (*589)
bas.termeulen@slaz.nl
B. Meulen, ter
Amsterdam 1064 AE
The Netherlands
020-5108911 (*589)
bas.termeulen@slaz.nl
Inclusion criteria
1. 18- 65 years of age
2. < 8 weeks sciatica
3. herniated disk on MRI as the cause of sciatica
4. correlation between symptoms and MRI findings
5. VAS 40 or more despite pain medication
Exclusion criteria
1. weakness graded MRC 3 or more
2. spine surgery at the same level
3. foraminal stenosis as the cause of symptoms
4. pregancy
5. severe comorbidity (e.g. cancer)
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| NTR-new | NL4218 |
| NTR-old | NTR4457 |
| Other | Wet commissie VUMC : WC2013-062 |
Summary results
Ter Meulen BC, Van de Vegt M, Wouda E et al. NTVG. submitted