No registrations found.
ID
Source
Brief title
Health condition
None
Sponsors and support
University Medical Center Groningen
For the NL part: University Medical Center Groningen
Intervention
Outcome measures
Primary outcome
Effect of tDCS on detection bias
Secondary outcome
Effect of tDCS on task sensitivity and raw false alarm rate
Background summary
Transcranial direct current stimulation (tDCS) is a noninvasive brain stimulation technique.Previously we effect of tDCS detection bias during signal detection task. The present study will replicate and extend a previous study into the effect of tDCS applied to the left superior temporal gyrus on basic auditory signal detection, as well as testing whether any effect is specific to speech-based stimuli. Control condition is now both placebo and active.
Study objective
1) There will be an effect of anodal stimulation to the left STG with reduced response bias on the signal detection task
2) This effect is specific for speech signal detection.
Study design
Participants recruitment immediately after METC approved;
2. Measurements finalized as soon as enough participants are found;
3. Primary and secondary outcomes up to 6 months after the data were collected for the last subject.
Intervention
transcranial direct current stimulation
Inclusion criteria
1) There will be a main effect of stimulation condition; specifically, that anodal stimulation to the left STG will lead to a reduced response bias (â, see section 2.6.1) on the signal detection task, compared to the other conditions.
2) We will also test for an interaction between stimulation condition and stimulus type; that is, to test for a difference in the effect of stimulation on response bias (â) to voice and tone stimuli. If any effect of stimulation is specific to voice stimuli, this would imply the effects are due to stimulation of language specific areas of cortex (e.g., Wernicke’s area). In contrast, if there is an effect of stimulation on all types of auditory signal detection, this would imply a more general effect of stimulation on auditory stimuli.
Exclusion criteria
1) (suspected) pregnancy
2) not signing the informed consent
3) family history of epilepsy
4) non-removable metallic objects on the head or arms,
5) a history of skin conditions (e.g., eczema).
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| NTR-new | NL6925 |
| NTR-old | NTR7121 |
| Other | : UMCG Research Register: 201700875 |