No registrations found.
ID
Source
Brief title
Health condition
Atrial fibrillation
Sponsors and support
Intervention
Outcome measures
Primary outcome
Correlation between speckle tracking determined global strain measurement and percentage of low voltage points in the left atrium.
Secondary outcome
-Recurrence of atrial fibrillation within 12 months after a blanking period of 3 months defined as registration of atrial fibrillation on ECG or episode lasting >30 seconds on Holter/Vitaphone recording.
-Correlation between strain/strain rate measurements and regional percentage of low voltage in the LA.;
-Correlation between laboratory values and voltage measurements
-Predictive value of strain/strain rate measurements and low voltage percentage for recurrent atrial fibrillation after catheter ablation.
-Quality of life before and after PVI measured with SF-12 questionnaire
Study objective
We hypothesized that there should be a relationship between LA structural remodeling assessed by invasive voltage mapping in the left atrium and LA functional remodeling assessed by strain and strain rate imaging in patients with AF.
Study design
1 year
Intervention
Measurement of left atrial voltage and echocardiographic strain measurements
T. Hesselink
Postbus 50 000
Enschede 7500 KA
The Netherlands
tel. (053) 487 2110
t.hesselink@mst.nl
T. Hesselink
Postbus 50 000
Enschede 7500 KA
The Netherlands
tel. (053) 487 2110
t.hesselink@mst.nl
Inclusion criteria
-Eligible to undergo percutaneous radiofrequent catheter ablation of atrial fibrillation.
-Sinus rhythm during echocardiography
-Age >18 years
-Expected follow up >12 months
Exclusion criteria
-Previous PVI or MAZE procedure.
-Emphysema
-Unable to provide informed consent.
-Pregnancy
-Presence of pacemaker or ICD
Design
Recruitment
Followed up by the following (possibly more current) registration
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| NTR-new | NL5074 |
| NTR-old | NTR5205 |
| CCMO | NL51350.044.15 |
| OMON | NL-OMON47852 |