Aim of the study is to answer the following questions:What is the influence of drinking different kinds of volumes on energy expenditure?What is the influence of drinking solutions with different osmolarities on the energy expenditure?Are changes in…
ID
Source
Brief title
Condition
- Appetite and general nutritional disorders
Synonym
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
energy expenditure
Secondary outcome
heart rate and blood pressure
finger tremor
temperature
Background summary
In western societies the prevalence of overweight and obesity is increasing.
Recent studies show that drinking of 0.5 L water increases energy expenditure.
The underlying mechanism is unknown. Two factors appear to play an important
role: volume and osmolarity of the drink. In this study the role of stretch
receptors and osmoreceptors in the thermogenic response after drinking will be
studied.
Study objective
Aim of the study is to answer the following questions:
What is the influence of drinking different kinds of volumes on energy
expenditure?
What is the influence of drinking solutions with different osmolarities on the
energy expenditure?
Are changes in energy expenditure associated with changes in heart rate and
finger tremor, as an index for activation of the sympathetic nervous system?
Study design
Double-blind, randomised cross-over design.
Intervention
The volunteers have to drink five different drinks:
1. 0,5 L water
2. 0,35 L water
3. 0,2 L water
4. 0,5 L 0,9% NaCl
5. 0,5 L 1,5% NaCl
Study burden and risks
no risks
Postbus 616
6200 MD Maastricht
Nederland
Postbus 616
6200 MD Maastricht
Nederland
Listed location countries
Age
Inclusion criteria
healthy volunteers, age 18-25 years
Exclusion criteria
medication use, under treatment of physician
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| CCMO | NL12166.068.06 |