While this survey will provide information about mean LDL-C levels and the percent of patients at LDL-C goals, the survey will also focus on HDL-C. A primary objective of this survey is to assess the levels of HDL-C in treated dyslipidemic patients…
ID
Source
Brief title
Condition
- Coronary artery disorders
- Endocrine and glandular disorders NEC
Synonym
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
Eveluation of the concentration of LDL-C, HDL-C, totaal cholesterol and
triglyceride in treated dyslipidemic patients in the US, Canada, Mexico,
Brazil, Netherlands, France, Spain, Taiwan and Korea.
Secondary outcome
see page 3 and 4 of the protocol
Background summary
Epidemiologic data clearly demonstrate that risk of coronary heart disease is
directly correlated with levels of LDL cholesterol (LDL-C) and inversely
correlated with levels of HDL cholesterol (HDL-C)
During treatment of dylipidemia patients the main goal is to achieve the LDL-C
values as described in the cholesterol management guidelines in order to
decrease the cardiovascular risk.
Little is known about physicians* adherence to cholesterol management
guidelines in daily practice.
The first L-TAP study showed that only 38% of the treated patients achieved the
LDL-C goal
Study objective
While this survey will provide information about mean LDL-C levels and the
percent of patients at LDL-C goals, the survey will also focus on HDL-C. A
primary objective of this survey is to assess the levels of HDL-C in treated
dyslipidemic patients, including patients attaining LDL-C treatment goals. This
will improve our understanding of the residual cardiovascular risk remaining in
patients treated with modern lipid modifying regimens by virtue of measuring
HDL-C levels in a large and geographically divers sample.
Study design
Patients will visit the hospital/ General physician just one visit.
During this visit Informed Consent will be documented, bloodpressure
measurement will be done, weight will be recorded and waist circumference will
be measured.
A blood sample will be taken, that will be analysed by a central lab.
All gathered data will be recorded in a Case Report Form.
Study burden and risks
The burden of the patients exists in a hospital visit where a bloodsample will
be taken. The risk will be the possibility of suffusion on the punture place.
Rivium Westlaan 142
2909 LD Capelle a/d IJssel
Nederland
Rivium Westlaan 142
2909 LD Capelle a/d IJssel
Nederland
Listed location countries
Age
Inclusion criteria
Patients older than 20 years of age
Exclusion criteria
recent trauma/ surgery; recent hospitalisation; acute infection which recuired anti-biotic treatment; pregnancy/ breastfeeding; myocardial infarction in the past 12 weeks.
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
Register | ID |
---|---|
CCMO | NL13214.015.06 |