1. To invest the prevalence of bacterial overgrowth in the elderly who undergo an diagnostic gastroscopy.2. After investigating the number of microorganisms in the aspirate the probable correlation will be established between the complaints of theā¦
ID
Source
Brief title
Condition
- Malabsorption conditions
Synonym
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
1. Numbers of bacteries in he aspirat from the gastric and duodenum about
10.5/ml aspirat
2. correlation with complaints
3. correlation with malabsorption
Secondary outcome
Which kind of bacteries are in the aspirat
Background summary
Elderly patients often present at geriatric departments with weightloss,
chronic diarrhea, cachexia and abdominal pain. Oftenly signs of malnourishment
are found during physical examination, laboratory work up (vitamins) or by
means of the mini nutritional assessment (MNA). There are many possible causes
for undernourishment in the elderly.
Bacterial overgrowth in the digestive tract, especially in the stomach and the
duodenum can cause the complaints of weight loss, chronic diarrhea, cachexia
and abdominal pain.
Certain factors probably predispose to bacterial overgrowth. These are slow
motility, diverticulosis, atrophic gastritis and certain drugs (PPI). In the
elderly these risk factors ocur frequently. Nevertheless bacterial overgrowth
in the digestive tract rarely is considered in the differential diagnosis.
It is important to know the prevalence of bacterial overgrowth in the elderly.
Treatment of bacterial overgrowth can consist of antibiotics and is easy to
perform.
Study objective
1. To invest the prevalence of bacterial overgrowth in the elderly who undergo
an diagnostic gastroscopy.
2. After investigating the number of microorganisms in the aspirate the
probable correlation will be established between the complaints of the patient
and bacterial overgrowth.
3.To invest if it is usefull to consider bacterial overgrowth as a possible
diagnosis.
4. To recognise the risk factors for bacterial overgrowth
5. Is bacterial overgrowth mainly caused by certain species, and if so which of
the bacteries is existing the most in the aspirat?
6. small bowel bacterial overgrowth as a diagnostic consideration?
Study design
We would like to invest the prevalence of bacterial overgrowth in patients with
gastric and/or bowel complaints who undergo a diagnostic gastroscopy.
With investigation in the patients file we try to find a correlation between
complaints of the patient and possible bacterial overgrowth.
Riskfactors will be investigated.
Study burden and risks
There is no extra risk
Louwesweg 6,
1066 EC amsterdam
Nederland
Louwesweg 6,
1066 EC amsterdam
Nederland
Listed location countries
Age
Inclusion criteria
1. men and women older then 70 years of age. 2).All patients who have an indication for gastroscopy because of there complaints. 3)Patients have to be competent and able to sign informed consent and agree to undergo gastroscopy.
Exclusion criteria
Patients who need gastroscopy in acute ilnesses
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
Register | ID |
---|---|
CCMO | NL12859.048.06 |