The objectives of this experiment are twofold. First, the muscle activation pattern related to a synergistic movement during reach is investigated, with attention for the existence of a threshold of amount of exertion above which an abnormal synergy…
ID
Source
Brief title
Condition
- Central nervous system vascular disorders
Synonym
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
The intensity of activation of 8 shoulder and elbow muscles is measured (by
surface EMG), to quantify movement control, along with kinematic parameters
(such as velocity and smoothness of movement), to quantify movement execution.
Secondary outcome
(not applicable)
Background summary
Arm function is often limited after stroke. Research has indicated that
abnormal, involuntary coupling between shoulder and elbow torques is involved.
Additionally, a proposed theory stated that in each stroke patient a threshold
exists, above which abnormal coupling (i.e. synergy) is expressed, related to
the extent of exertion. However, the expression of these abnormal synergies in
muscle activity and the existence of an intensity-related threshold is not
known yet. Furthermore, not much knowledge exists about the behaviour of these
synergies with different velocities of movement. Information about these
underlying muscle activition will provide a better insight in movement control
after stroke, which may offer points of impact for new applications in
rehabilitation for recovery of arm function after stroke.
Study objective
The objectives of this experiment are twofold. First, the muscle activation
pattern related to a synergistic movement during reach is investigated, with
attention for the existence of a threshold of amount of exertion above which an
abnormal synergy manifests. Second, the relationship between iso-metric and
iso-kinetic movement executions is determined.
Study design
Muscle activation during a synergistic movement is compared with a movement
without coupling in a cross-sectional experiment of repeated movements. The
synergy is provoked by providing resistance against shoulder abduction, during
a reaching movement laterally and upward to shoulder height, with 4 different
intensities of resistance (with a maximum of 60% of the individually generated
maximal torque).
Additionally, isokinetic elbow extensions (at 4 different speeds) are compared
to isometric performance. This is repeated 7 times, in which the amount of
generated shoulder abduction is varied in equal steps from 0 to 200% of the
weight of the arm.
Study burden and risks
The risks for the subject are limited to a minimum, since the movement tasks
represent functional and familiar arm movements and are performed only within
the scope of the subject*s ability. Furthermore, the Dampace device can never
provoke movements outside the subject*s range of motion, since it can only
resist movement that is generated by the subject and can not move the arm of
the subject on its own.
Roessingsbleekweg 33b
7522 AH Enschede
Nederland
Roessingsbleekweg 33b
7522 AH Enschede
Nederland
Listed location countries
Age
Inclusion criteria
For both stoke patients and healthy subjects:
-Aged between 25 and 75 years
For stroke patients only:
-Stroke at least 6 months prior to admittance to experiment
-Right upper extremity affected (due to experimental set-up only for right arm)
-Score of 0 or 1 on item AIII-2 of Fugl-Meyer assessment:
= anteflexion of the arm from 0° to 90° with full extension of the elbow and the lower arm midway between pro-/supination; performance must be without elbow flexion immediately at the start of movement
-Having (received) treatment at the Roessingh Centre of Rehabilitation
Exclusion criteria
For both patients and healthy volunteers:
-Shoulder pain, either in rest or in movement
-Additional neurologic, orthopaedic or rheumatologic disease of right upper extremity, likely to interfere with mobility and/or strength of the arm
-Inability to understand and follow instructions
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| CCMO | NL12726.080.06 |