A better understanding of the pathology of PPP, in particular the mechanisms responsible for the problems with hip flexion
ID
Source
Brief title
Condition
- Musculoskeletal and connective tissue deformities (incl intervertebral disc disorders)
Synonym
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
1. Questionnaires
2. Anamnesis and physical examination by the orthopaedic surgeon
3. The H-reflex of the m. rectus femoris
4. Kinematics of Active Straight Leg Raising:
how high can participants raise the leg, how long can they keep the leg in
that
position, is this dependent on experimental condition?
5. Muscle activity during Active Straight Leg Raising:
relative timing, amplitude, dependence on experimental condition
6. Gait kinematics on the treadmill
what are maximal and comfortable walking velocity, what are the relative
phases
of horizontal rotations during walking, what is the step frequency, how are
these
dependent on experimental condition?
7. Muscle activity durinig walking on the treadmill
relative timing, amplitude, dependence on experimental condition
Secondary outcome
Relationships between primary study parameters--such as relative timing of hip
flexors with respect to transverse abdominal muscles.
Background summary
About 12.5% of all pregnant women, and 2.5% of all women postpartum, suffer
from Pregnancy-related Pelvic girdle Pain (PPP) that is serious enough to
warrant medical attention. More than 99% of the cases recover spontaneously,
but still, many women suffer from it for some time during their lives, and in
some, the problem turns chronic. Most women with PPP have trouble flexing their
hip, stating that it feels as if something "stops" the movement, or that it is
"as if the leg is paralysed". So far, no research has been performed to
elucidate the underlying mechanisms of these problems with hip flexion.
Study objective
A better understanding of the pathology of PPP, in particular the mechanisms
responsible for the problems with hip flexion
Study design
We will invite women with PPP (six weeks postpartum) to perform Active Straight
Leg Raising under 3 different conditions (normal, with weights attached to the
lower legs, and with a pelvic belt), and to walk on a treadmill under 2
conditions (normal, with a pelvic belt). We will measure the activity of a
large number of muscles (3 deep muscles, with fine wire EMG, and 15 superficial
muscles, with surface electrodes), and during gait we will determine 3D full
body kinematics. Moreover, participants fill-in questionnaires (SF-36 and
Tampa), are seen by an orthopaedic surgeon (anamnesis plus physical
examination), and the H-reflex of the m. rectus femoris is determined by a
clinical neurophysiologist.
Study burden and risks
The study will cost participants about half a day. Experimental Straight Leg
Raising and walking on the treadmill will be as painful or difficult as it is
for the participants in their deaily life; they are, however, always allowed to
indicate that, for instance, a certain walking velocity is too high for them,
and then we stop.
Inserting the wire electrodes will probably be an unusual sensation. It is
possible that some participant will experience pain and/or numbness. If that
happens, the electrodes are immediately removed. The literature did not report
any lasting damage.
de Boelelaan 1117
1081 HV Amsterdam
Nederland
de Boelelaan 1117
1081 HV Amsterdam
Nederland
Listed location countries
Age
Inclusion criteria
pregnancy-related pelvic girdle pain arose during pregnancy or just after delivery and is still present 6 weeks after delivery
Exclusion criteria
other locomotor pathology that would affect walking
cardiac or pulmonary problems that would affect walking
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| CCMO | NL13908.029.06 |