Measurement of the growth of the eye of children with unilateral cataract.
ID
Source
Brief title
Condition
- Congenital eye disorders (excl glaucoma)
Synonym
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
Significant difference in eye axis between experimental group and control.
Secondary outcome
Significant difference in eye axis between experimental groups.
Background summary
Developmental processes depend on internal as well as on external factors, with
infancy (age upto eight years) being a critical period. Sensory deprivation,
for instance, can affect the eye with respect to morphology and functioning.
Cataract is diagnosed in children of various ages and standard treatment
implies surgical removal of the affected lens. Depending on eye condition, an
artificial Intra-Ocular Lens (IOL) may be inserted to replace the original one.
Examination of developmental progress of the operated infant eye will increase
knowledge of the underlying mechanism and time course of ocular maturation.
This may help to improve the ophthalmologist*s assessment of best treatment
and/or prospect of pediatric cataract.
Study objective
Measurement of the growth of the eye of children with unilateral cataract.
Study design
Retrospective, non-randomized.
Study burden and risks
This type of developmental research can only take place with children.
Participants of this study do not benefit from the results of this study. Risks
are negligible; burden comprises 1 visit of 30 minutes to the Rotterdam Eye
Hospital.
Initial measurement of eye axis was performed by echo oculometry (requiring
direct contact with the cornea) at the time of surgery and, thus, under
anesthesia. Methodological consistency would be optimal if this measurement
were repeated, but for ethical reasons (minimal discomfort for patients) and
for practical reasons (maximal number of children cooperating) the second
measurement will be done with a non-contact technique.
Schiedamse Vest 180
3011 BH Rotterdam
Nederland
Schiedamse Vest 180
3011 BH Rotterdam
Nederland
Listed location countries
Age
Inclusion criteria
- Informed consent.
- Unilateral congenital cataract.
- Unilateral traumatic cataract.
- Age < 6 years at the time of cataract surgery.
- If IOL implant not concurrent with cataract extraction: eye growth until implant.
Exclusion criteria
- Reluctance to cooperate.
- If IOL implant not concurrent with cataract extraction: eye growth since implant.
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
Register | ID |
---|---|
CCMO | NL14857.078.06 |