Analysis of the effects of the Twin-Pulse Life Support on on the systemic inflammatory response and the effect on microvascular blood flow in ocmparison to standard used Extracorporeal Circuit Device
ID
Source
Brief title
Condition
- Myocardial disorders
- Cardiac therapeutic procedures
Synonym
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
Systemic inflammatory response
Secondary outcome
Analyses of the effect of Twin-PulseLifeSupport on microvascular blood flow
Background summary
the Twin-Pulse Life support is an extracorporeal circulation which uses a
pulsating mechanism, which is suggested to have positive effect on the systemic
inflammatory response and which could lead to a better microvascular blood
flow.
T-PLS coul be an emergency treatment in case of severe cardiac or pulmonary
failure.
Study objective
Analysis of the effects of the Twin-Pulse Life Support on on the systemic
inflammatory response and the effect on microvascular blood flow in ocmparison
to standard used Extracorporeal Circuit Device
Study design
Randomized prospective clinical trial
Study burden and risks
no additional risks compared to the standard used heart-lung machine, such as
pump stop or oxygenator failure.
P. Debyelaan 25
6229 HX Maastricht
Nederland
P. Debyelaan 25
6229 HX Maastricht
Nederland
Listed location countries
Age
Inclusion criteria
primary CABG
age: 55 - 75 years
left ventricular ejection fraction > 45%
Exclusion criteria
renal dialysis
history of stroke
pulmonary insufficiency
Design
Recruitment
Medical products/devices used
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| CCMO | NL14737.068.06 |