1) To examine whether adolescents with depression, show abnormalities during specific attentional processes, compared to normal controls, 2) To determine whether abnormalities in attentional processes can be considered as prognostic markers of a…
ID
Source
Brief title
Condition
- Mood disorders and disturbances NEC
Synonym
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
Scores on questionnaires (SDQ, BDI-II-NL, Quick Big Five, Conners, CRSS,
PSWQ-C) to assess the severity of depression symptoms and potential
confounders. Scores on (experimental) attentional computerized tasks (reaction
times, numbers of misses) and one questionnaire (attentional control) to assess
attentional processes. At follow-up after twelve months, scores on
questionnaires (total and factor scores, see above) and computer tasks are
assessed.
Secondary outcome
n.v.t.
Background summary
The relation between attentional processes and depression is not yet clear.
Depression seems to be related to impaired attentional functioning. Attentional
processes contribute to self-regulation in a broad sense, as it enables people
to amplify or weaken thoughts, emotions and behavior. Impaired control over
attentional processes can complicate daily functioning. Problems can occur in
the allocation and disengagement of attention, but also in inhibition of
irrelevant negative stimuli. Until now, attentional problems in relation to
depression have hardly been studied in an adolescent population.
Study objective
1) To examine whether adolescents with depression, show abnormalities during
specific attentional processes, compared to normal controls, 2) To determine
whether abnormalities in attentional processes can be considered as prognostic
markers of a vulnerability for (the maintenance of) depression (with a follow
up time interval of twelve months).
Study design
Mixed design (both cross-sectional and prospective)
Study burden and risks
Total study load per participant: 5 hours maximum
All measures have already been applied in depressed samples and no report of
problems was found in the literature. Most adolescents enjoy the computer
tasks. The experiments with affective stimuli contain as many negative as
positive stimuli. If any severe emotional problems will be present during the
phases of this study, a psychiatrist of Karakter University Centre can be
consulted. Subjects can stop participating at any time of the study.
Benefit: Facilitation of referral to mental health care
Group relatedness:
This study is group- and age-related, because abnormalities in attentional
processes as a marker of a vulnerability for (the maintenance of) depression
cannot be studied in healthy nondepressed subjects. Furthermore, the study
focusses on depression in adolescence because the incidence of depression in
this agegroup increases and needs to be studied in relation to attentional
problems.
Postbus 9101
6500 HB Nijmegen
Nederland
Postbus 9101
6500 HB Nijmegen
Nederland
Listed location countries
Age
Inclusion criteria
group 1: depressive symptoms in clinical range
group 2: all symptoms scores in normal range
Exclusion criteria
group 1: externalizing symptoms in clinical range
group 2: depressive symptoms in clinical range
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| CCMO | NL15521.091.06 |