The aim of this study is to describe the values of the SNIP in patients with neuromuscular disease and various respiratory conditions and to assess the practicability of the SNIP in these patients.
ID
Source
Brief title
Condition
- Muscle disorders
- Neuromuscular disorders
Synonym
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
Description of the values of the SNIP in patients with neuromuscular diseases.
The feasibility of the SNIP in patients with neuromuscular disease in
comparison with the VC and MIP.
Secondary outcome
The feasibility of the SNIP in children and ALS patients in comparison with the
VC and MIP.
The practicality of the SNIP from the perspective of the patient and the
performer of the tests.
Background summary
The SNIP is novel test for measuring the inspiratory muscle strength. The
drawback of usual tests, like the vital capacity (VC) and maximal inspiratory
pressure (MIP), is that low values may occur due to submaximal effort, or air
leaks rather than respiratory muscle weakness. The SNIP is a natural manoeuvre
and therefore easier to perform and less unpleasant than the MIP.
Study objective
The aim of this study is to describe the values of the SNIP in patients with
neuromuscular disease and various respiratory conditions and to assess the
practicability of the SNIP in these patients.
Study design
It is a pilot study with a quantitative , descriptive, cross-sectional design
Study burden and risks
De SNIP is measured in an occluded nostril during a maximal sniff manoeuvre
through the contralateral nostril. The plug is connected by means of a
catheter with a pressure monitor. Patients will perform a maximum of 5 sniffs.
The test will take in total five minutes maximally. After the test the patient
will answer 6 questions about the performance of the SNIP.
Heidelberglaan 100
3584 CX Utrecht
Nederland
Heidelberglaan 100
3584 CX Utrecht
Nederland
Listed location countries
Age
Inclusion criteria
Neuromuscular disease with a risk of nocturnal hypoventilation
Exclusion criteria
Home mechanical ventilation
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| CCMO | NL16492.041.07 |