To investigate the association between AGE, COPD severity and number of packyears.
ID
Source
Brief title
Condition
- Bronchial disorders (excl neoplasms)
Synonym
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
- AGE reading
- COPD (GOLD stadia) (Pulmonary function : FEV1, FVC, Tiffeneau index)
- Packyears
Secondary outcome
- Age
- number of exacerbations
- BMI
Background summary
The AGE (Advanced Glycation Endproducts) reader is a noninvasive device based
on autofluorescense of the skin. AGE reflects metabolic and oxidative stress.
Research showed that AGE is a predictor of complications in diabetic patients
and in patients with nephropathy. Until now, the relation between AGE and
severity of pulmonary disease has not been studied. In addition, there may be a
relation between AGE and number of packyears without decline in lungfunction.
Therefore in this study we want to investigate the association between AGE,
COPD severity and number of packyears. In future AGE may be helpful as
predictor of morbidity and mortality in patients with COPD.
Study objective
To investigate the association between AGE, COPD severity and number of
packyears.
Study design
Observational study
Study burden and risks
No burden, no risk.
Time per participant 5-10 minutes
Hanzeplein 1
9713 GZ
Nederland
Hanzeplein 1
9713 GZ
Nederland
Listed location countries
Age
Inclusion criteria
COPD and or smoking history
minimum age: 18 years
Exclusion criteria
age < 18 years
Design
Recruitment
Medical products/devices used
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| CCMO | NL17533.042.07 |