Main question:Does a restrictive fluid management during general anesthesia lead to less urinary production?Sub questions:Does a fluid management with colloid fluid during general anesthesia lead to a change in urinary production?Does a different…
ID
Source
Brief title
Condition
- Therapeutic and nontherapeutic effects (excl toxicity)
- Urinary tract signs and symptoms
- Therapeutic procedures and supportive care NEC
Synonym
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
urinary production
Secondary outcome
bloodpressure, heart rate
Background summary
Hypotension due to vasodilatation or hypovolemia is a common complication
during general anesthesie. This is treated by infusion of fluids or
vasopressive medication.
Urinary retention is a known postoperative complication after spinal anesthesia
but is also seen after general anesthesia. Risk factors for this complication
are for example age, duration of surgery or the given amount of fluid.
Unexpected bladder distention is sometimes found in patients who did not seem
to be at risk for urinary retention given the duration of surgery or the given
amount of fluid. The effect of general anesthesia and the infusion of different
kinds of fluid on urinary output and course of diuresis is unknown
In this study we would like to investigate whether there is a correlation in
fluidmanagement and hemodynamics under general anesthesia and total
perioperative urinary output, to eventually prevent bladderdistention.
Study objective
Main question:
Does a restrictive fluid management during general anesthesia lead to less
urinary production?
Sub questions:
Does a fluid management with colloid fluid during general anesthesia lead to a
change in urinary production?
Does a different kind of fluidmanagement lead to a difference in hemodynamics
during general anesthesia?
Study design
prospective, randomised single-blind study
Study burden and risks
questionary preoperative screening
questionary preoperative
bladderscan preoperative
questionary thirst/bladderdistention/urge every half hour postoperative
(minimum of 4 times)
bladderscan every half hour (minimum of 4 times)
collection of urine in case of spontaneuous urination
risks:
the standard risks of general anesthesia like hypotension, hypovolemia.
Wagnerlaan 55
6800 TA Arnhem
Nederland
Wagnerlaan 55
6800 TA Arnhem
Nederland
Listed location countries
Age
Inclusion criteria
outpatient treatment under general anesthesia
Exclusion criteria
laparoscopic procedures, patients with a history of mental, hepatic, renal, spinal or neurologic disorders, use of medication, urinary tract disorders
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
Register | ID |
---|---|
EudraCT | EUCTR2007-002483-10-NL |
CCMO | NL16685.091.07 |