The objective of the study is to determine if a 3D motion platform (to measure vestibular function) and accelerometry and a insole pressure system (to measure balance) can be used in future research on patients with vestibular lesions. For this, we…
ID
Source
Brief title
Condition
- Inner ear and VIIIth cranial nerve disorders
Synonym
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
Feasibility of a moving platform to measure vestibular function, and
accelerometry and an insole pressure device to measure balance of patients with
vestibular schwannoma.
Vestibular function: 3D motion platform
Balance: Berg balance scale, accelerometry, insole pressure device
Secondary outcome
Patient characteristics (e.g. age, gender) and disease characteristics (e.g.
tumor size) will be registered.
Background summary
Vestibular lesions lead to balance problems and vertigo. This has a major
influence on the patient*s daily functioning. It is estimated that 40% of
people older than 40 years have balance problems and vertigo of which 35-55%
have a peripheral vestibular lesion. Although vestibular rehabilitation is
recommended to facilitate recovery, the therapy effect shows large differences
between the patients with vestibular lesions. A possible reason for these
differences in therapy effect could be that current clinical vestibular
function and balance tests can not discriminate properly between patients that
recover full, less or not at all after receiving vestibular rehabilitation. A
solution might be to use more advanced techniques to measure vestibular
function and balance. Before this, we have to know whether it is feasible to
use these techniques on patients with vestibular lesions.
Study objective
The objective of the study is to determine if a 3D motion platform (to measure
vestibular function) and accelerometry and a insole pressure system (to measure
balance) can be used in future research on patients with vestibular lesions.
For this, we evaluate the feasibility and discriminative value of these
measurement techniques.
Research questions:
1. Is it feasible to measure the vestibular function with a 3D motion platform,
and balance with accellerometry and an insole pressure system of patients with
a vestibular schwannoma?
2. Can a 3D motion platform, regarding vestibular function, and accellerometry
and an insole pressure system, regarding balance, discriminate better than
current clinical tests between a) healthy persons and patients with an
vestibular lesion and b) between different patients with an vestibular lesion?
Study design
It is a cross-sectional study design. Five patients with vestibular schwannoma
and balance problems receiving radiation therapy and 5 healthy controls are
selected to participate. Vestibular function is measured by a moving platform,
and balance is measured by accelerometry and an insole pressure device. The
feasibility to perform these measurements is evaluated by questionnaires for
the participants and the researchers. All measurements are performed once.
Study burden and risks
The vestibular and balance tests are not painful or harmfull.
For the vestibular test, contact lenses are placed on the eye with a drop of
mimins (oxybuprocaine). 25 years of experience exists with this procedure.
Vertigo elicit by the vestibular test with the movement platform dissapears
soon after this test.
During the balance measuremenets, patients are continuously watched by a
researcher or therapist. The risk of falling is, therefore, negligible.
Patients with severe balance problems do not perform balance tests with their
eyes closed.
Postbus 2040
3000 CA Rotterdam
Nederland
Postbus 2040
3000 CA Rotterdam
Nederland
Listed location countries
Age
Inclusion criteria
- patients with vestibular schwannoma
- vertigo
- balance problems
- no cerebellar problems
- written informed consent
Exclusion criteria
- patients with vestibular schwannoma who receive other treatment than radiation
- heart disorders
- pregnancy
- not understanding the Dutch language
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
Register | ID |
---|---|
CCMO | NL20322.078.08 |