Determining the prevalence of testicular microlithiasis in Down syndrome.
ID
Source
Brief title
Condition
- Testicular and epididymal disorders
Synonym
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
The prevalence of testicular microlithiasis in Down syndrome.
Secondary outcome
Volume and position of both testes.
Background summary
Testiculair microlithiasis is an entity characterized by calcifications in the
seminiferous tubule of the testis (-es). It is readily diagnosed by the
ultrasonographic appearance of small hyperechoic foci typically scattered
throuhout the testis. Apparently asymptomatic in itself and often an incidental
finding. Testicular microlithiasis is associated with benign states as well as
pathological conditions. Clinical concern is primarily focused on the high
association of testicular cancer with testicular microlithiasis. Since the
incidence of testicular tumors appears to be increased in Down syndrome,
testicular microlithiasis in Down syndrome has particular interest.
Study objective
Determining the prevalence of testicular microlithiasis in Down syndrome.
Study design
The prevalence of testicular microlithiasis and the volume of both testes (from
patients with Down syndrome whose ages ranges from 0-25 years) will be
determined using ultrasonography. The results will be noted on a apart form and
the data will be recorded in a statistical program.
Study burden and risks
The risks associated with participation are minimal.
Wilhelminaan 12
1815 JD Alkmaar
Nederland
Wilhelminaan 12
1815 JD Alkmaar
Nederland
Listed location countries
Age
Inclusion criteria
Boys/ men with down syndrome confirmed by chromosomal evaluation.
Age: 0 - 18 years.
Exclusion criteria
Disorders of the testes/ scrotum (torsio testis, hydrocele)
Operations of the testis (-es) in thepast, like torsio testis, undescended testis.
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| CCMO | NL21126.094.07 |