To investigate the association of anatomical defects with the occurrence of stress urinary incontinence.
ID
Source
Brief title
Condition
- Tendon, ligament and cartilage disorders
- Pregnancy, labour, delivery and postpartum conditions
Synonym
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
Stress urinary incontinence at 12 and 36 weeks of gestation and 6 months
postpartum.
Secondary outcome
Association between anatomical and mobility disorders of the levator ani
complex and other urogenital symptoms.
Association between pregnancy and childbirth related factors and the presence
of levator injuries
Background summary
Urinary incontinence (UI) is a common problem in adult women, with an
estimated prevalence that ranges between 25 and 60%. Childbirth has been shown
to be one of the major risk factors for developing urinary incontinence. Almost
half of incontinent women suffer from urine loss during physical exercise, the
so-called Stress Urinary Incontinence (SUI). This SUI is caused by the
occurrence of insufficient support of the urethra, but its pathophysiology has
not been fully elucidated. There is little information on the association
between the occurrence of SUI and anatomical injuries caused by pregnancy
and/or delivery.
Study objective
To investigate the association of anatomical defects with the occurrence of
stress urinary incontinence.
Study design
prospective observational study
Study burden and risks
The extent of burden for participating women will be minimal. During the
routine prenatal care and the visit at 6 months postpartum, an additional
ultrasound will be performed. Ultrasound examination will take 10-15 minutes.
Adverse effects of ultrasound during pregnancy are not described.
Heidelberglaan 100
3584 CX Utrecht
NL
Heidelberglaan 100
3584 CX Utrecht
NL
Listed location countries
Age
Inclusion criteria
nulliparous women
singleton pregnancy
good knowledge of Dutch language
Exclusion criteria
History of urinary and or faecal incontinence
Previous prolapse or anti-incontinence surgery
Connective tissue disease
Neurological disorders
Not allowed to do a maximum valsalva manoeuvre
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| CCMO | NL22685.041.08 |