The goal of this research is to see whether offering fluoride three times a day enhances the remineralisation of an early cariouslesion more than fluoride twice a day.
ID
Source
Brief title
Condition
- Other condition
Synonym
Health condition
caries
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
mineralisation of enamel/dentine
difference in fluorescence
level of fluoride in enamel/dentine
Secondary outcome
amount of fluoride of dental plaque and saliva
Background summary
To patients that are at high risk of getting caries, dentists often reccomend
an extra period of fluoride exposure a day, besides the usual brushing of the
teeth with a fluoride dentifrice twice a day. It was already demonstrated that
the surface of a tooth contains more fluoride after additionally rinsing with a
fluoride mouthrinse. It is not shown that it as well enhances the
remineralisation of an early cariouslesion. We will investigate that in this
study.
Study objective
The goal of this research is to see whether offering fluoride three times a day
enhances the remineralisation of an early cariouslesion more than fluoride
twice a day.
Study design
In the buccal flanges of the partial prosthesis in the lower jaw of the
participants, specimens of enamel or dentine will be placed. On the specimens
an early carious lesion is made. The participants need to follow an oral
hygiene protocol that says they have to brush twice a day with fluoride
toothpaste and rinse with a fluoride- or a control mouthrinse. After the
experimental period the specimens will be removed from the prosthesis an
analysed for the mineral content. Besides this, samples of saliva and plaque
will be taken to analyse the amount of fluoride.
Intervention
Participants brush there teeth twice a day with a fluoride dentifrice and
additionally rinse with a fluoride- or control mouthrinse once a day.
Study burden and risks
The burden is the extra visits to the clinic and executing the oral hygiene
protocol (which people normally already execute for most part). Participating
means no health risks for the participants.
Leeuwenveldseweg 5N
1382 LV Weesp
Nederland
Leeuwenveldseweg 5N
1382 LV Weesp
Nederland
Listed location countries
Age
Inclusion criteria
partial prosthesis on the lower jaw
enough thickness of the resin of the prosthesis
age > 18 years
Exclusion criteria
not enough thickness of the resin of the prosthesis
not being able to deal with the oral hygiene protocol
no partial prosthesis in the lower jaw
age < 18
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| CCMO | NL19894.029.07 |