Prospectively compare the sensitivity of 2D DSA and 3D rotational angiography in the detection of intracranial aneurysms.
ID
Source
Brief title
Condition
- Aneurysms and artery dissections
Synonym
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
Comparing the number of detectable aneurysms on 2D DSA and 3D rotational
angiography.
Secondary outcome
NVT
Background summary
Recently, we performed a retrospective study comparing sensitivity of 2D versus
3D rotational angiography in the detection of intracranial aneurysms. This
study showed that approximately 20% of aneurysms were missed on 2D images
alone. The aim is to design a prospective study comparing these imaging
modalities in the detection of intracranial aneurysms.
Study objective
Prospectively compare the sensitivity of 2D DSA and 3D rotational angiography
in the detection of intracranial aneurysms.
Study design
Location: Elisabeth ziekenhuis Tilburg
Name of the study: Additional value of 3D rotational angiography in the
detection of intracranial aneurysms.
Duration: from 1/10/2008 to 1/10/2009
Including 100 patients.
Reading of the 2D and 3D images independently by two independent radiologists.
Standard imaging protocol:
selective angiography of left internal carotid artery, right internal carotid
artery en left vertebral artery. In case the right posterior inferior
cerebellar artery is not visible also a selective angiogram of the right
vertebral artery is performed.
Additional 3D rotational angiography in case of suspected aneurysm on 2D DSA or
on basis of SAH distribution on CT.
Angiographic imaging in research setting:
Same as standard imaging protocol supplemented with standard 3D rotational
angiography of both internal carotid arteries as well as one vertebral artery.
Study burden and risks
The total length of the total study increases by 10 minutes. There will be
about 0,4 mSv extra radiation dose and approx. 30 ml extra contrast given to
the patient. The extra radiation dose as well as the extra contrast dose are
very low and will not form a health risk for the patient.
Hilvarenbeekseweg 60
5022 GC Tilburg
Nederland
Hilvarenbeekseweg 60
5022 GC Tilburg
Nederland
Listed location countries
Age
Inclusion criteria
patients with a suspected intracranial aneurysm
Exclusion criteria
Age < 18 years
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| CCMO | NL21972.008.08 |