This study will investigate the possibility to use a physical and/or cognitive 2 bout exercise test to evaluate recovery/fitness of the subjects.
ID
Source
Brief title
Condition
- Other condition
Synonym
Health condition
inadequaat herstel (overreaching)
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
It is expected that sleep deprivation combined with strenuous exercise will
increase the difference between the first and second bouts of cognitive and
physical tests, which will result in differences in hormone level, oxidative
stress and activity of the autonomic nervous system.
Secondary outcome
Oxidative stress parameters and immune function are followed in time to
evaluate use of these as indicators for recovery. They will be compared with
the results of differences in hormone levels and autonomic nervous system.
Background summary
Military people on a mission are subjected to physical exercise and cognitive
tasks. During and between missions both tasks can lead to fatigue, but there
are no objective tests to determine recovery / fitness of the military people.
Objective tests to estimate the status of recovery / fitness of a person can be
used as a tool to prevent a subject from more training (resulting in
overtraining) or going on a mission.
Study objective
This study will investigate the possibility to use a physical and/or cognitive
2 bout exercise test to evaluate recovery/fitness of the subjects.
Study design
The study is designed as a repeated measurements test. All subjects will follow
the same procedures. The study will be conducted within approximately 32 hours.
72 hours after the start of the experiment subjects will return to TNO for a
sample of blood, urine and exhaled breath.
Intervention
All subjects will receive the following study procedures: a repeated two bout
VO2max tests with cognitive tests and exhaled breath and blood pressure
measurements. Subjects will not sleep during one night. During the night and
during the next morning the subjects will perform a 10 minutes time trial on a
bicycle ergometer.
Study burden and risks
Before the study, subjects will be screened, based on their medical history, to
ascertain their health. After the screening, the subjects will visit TNO two
times. Four VO2max tests within 24 hours combined with sleep deprivation and
sub maximal exercise will induce fatigue and will not allow total recovery, but
are not too strenuous for trained young and healthy subjects.
Kampweg 5
3769 ZG
Nederland
Kampweg 5
3769 ZG
Nederland
Listed location countries
Age
Inclusion criteria
- male
- 18-35 years of age at the start of the experiment
- well trained (at least training 2 times a week and participation in competative sports)
- non smoker (or stopped at least 2 years ago)
- familiar with VO2-max tests
Exclusion criteria
1 Participation in any clinical trial including blood sampling and/or administration of substances up to 30 days before Day 01 of this study
2 Having a history of medical or surgical events that may significantly affect the study.
3 Prescribed medication that may interfere with the study outcome
4 Alcohol consumption >28 units/week
5 Not having a general practitioner
6 Not willing to accept information-transfer concerning participation in the study, or information regarding his/her health, findings at anamnesis or physical examination and eventual adverse events to and from his general practition
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| CCMO | NL26047.028.08 |