The primary goals is to determine the thermophysiological strain during the 7-hills run. Specifically, we are interested in those subjects with a core body temperature above 40 degrees. Based on additional research, we aim to gain better insight…
ID
Source
Brief title
Condition
- Other condition
Synonym
Health condition
hitte-gerelateerde problemen tijdens fysieke inspanning
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
- core body temperature
- fluid intake and toilet visits
When a core body temperature above 40 degrees is recorded:
- bloed (10 ml venous) and urine assessments of electrolytes (sodium)
Secondary outcome
- Heart rate
- Clothing
Background summary
Past years, a large number of participants of endurance athletic events
(marthons of Rotterdam-London-Boston, dam-tot-dam-loop) ended up in hospital,
primarily because of heat-related problems. To the best of our knowledge, only
little is known about the impact of endurance events on the thermoregulation.
Based on a pilot study, core body temperature during the 7-hills run increases
to 39.4 degrees, with some individuals demonstrating an increase above 40
degrees. In general, we aim to gain better insight into the impact of the
7-hills run upon the thermophysiological strain. Specifically, we aim at those
subjects that finish the 7-hills run with a core body temperature above 40
degrees. This groups is predisposed to develop (serious) heat-related problems.
After identification of these subjects, additional tests will be performed to
gain insight into the electrolyte and fluid balance. A fluid disbalance is
suggested to be crucial in the development of clincial symptoms and problems
when core body temperature rises. This information is essential to prevent and
treat heat-related problems during endurance events.
Study objective
The primary goals is to determine the thermophysiological strain during the
7-hills run. Specifically, we are interested in those subjects with a core body
temperature above 40 degrees. Based on additional research, we aim to gain
better insight into the fluid and electrolyte balance, which may relate to the
heat-related problems in these subjects with core body temperatures above 40
degrees.
Study design
Observational study
Study burden and risks
In addition to a questionnaire, heart rate monitor and determination of body
weight, subjects receive a sensor pill that record core body temperature. The
latter assessment is a safe, valid and 'friendly' method to record core body
temperature. The burden of these tests are, physical as well as in time,
minimal and privide important information which is necessary for the primary
aim of the study.
In the subpopulation of subjects with a core body temperature above 40 degrees,
blood and urine will be taken to gain insight into the fluid and
electrolytebalance. This is a minimally invasive burden for the subjects, while
it provides important information.
Geert Grooteplein-noord 21
6525 EZ Nijmegen
NL
Geert Grooteplein-noord 21
6525 EZ Nijmegen
NL
Listed location countries
Age
Inclusion criteria
- older than 18
- participant of the 7-hills run
Exclusion criteria
obstructive disease of the gastro-intestinal tract, including diverticulitis and inflammatory bowel disease
- previous gastrointestinal surgery, except cholecystectomy and appendectomy
- MRI during the period that the CorTemptm sensor is within the body (e.g. 1 day preceding the 7-hills run, the day of the 7-hills run and 2 days after the 7-hills run)
- subject having a cardiac pacemaker or other implanted electromedical device.
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| CCMO | NL24437.091.08 |