Evaluation of function of maxillectomy patients after prosthetic obturation, related to the extent of the defect.
ID
Source
Brief title
Condition
- Miscellaneous and site unspecified neoplasms malignant and unspecified
- Head and neck therapeutic procedures
Synonym
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
Primary outcome measurements:
- nasalance on a VAS score
- maximal mouthopening
- mixing ability index
- quality of life and obturator functioning questionnaires
stratified for:
- size of maxilla defect (Brown classification)
- remaining percent hard palate and soft palate contralaterally
- resection of the premaxilla
- history of adjuvant radiotherapy
- presence of natural dentition
Secondary outcome
Primary outcome measurements stratified for:
- age
- sex
Background summary
Patients are after a maxillectomy often reconstructed with a prosthetic
obturator. This is a simple and effective way to fill up the defect that exists
after tumorablative surgery and to prevent problems with eating and speaking.
There is relatively little literature about the function after such a
reconstruction. Some small studies with confined patient groups show that
function is well recovererd after surgery, but extent of the resection
influences the functional result.
Nowadays, there is a second curative therapy modality for patients with head
and neck cancer, namely organsparing therapy, chemoradiation. Inoperable tumors
are being treated with curative chemoradiation, but some patients will be
advised primary chemoradiation if the tumor is so large that after extensive
surgery a big functional loss may be expected. This is called functional
inoperability.
In order to make a careful patient selection for different treatment options,
and to be able to provide meaningful preoperative patient counselling about the
expected postoperative result after a maxillectomie, we aim at evaluating
functionality after a maxillectomy and prosthetic rehabilitation. The function
will be related to the extent of resection, dentition and a history of probable
adjuvant radiotherapy, in order to find significant anatomic and preoperatively
known patient-bound factors that deteriorate function, namely mastication,
nasalance, trismus and quality of life.
Study objective
Evaluation of function of maxillectomy patients after prosthetic obturation,
related to the extent of the defect.
Study design
Retrospective cohort study
Study burden and risks
Burden for participating patients is an extra visit to the Antoni van
Leeuwenhoek Hospital, once only, lasting 30 minutes. There is no extra risk
involved.
p.a. A.J.M. Balm, Hoofd hals chirurg, Plesmanlaan 121
1066 CX Amsterdam
Nederland
p.a. A.J.M. Balm, Hoofd hals chirurg, Plesmanlaan 121
1066 CX Amsterdam
Nederland
Listed location countries
Age
Inclusion criteria
Patients
- having undergone a maxillectomy 1998-2008
- reconstructed with an obturator
- controlled by the dentists/ maxillofacial prosthetics of the Antoni van Leeuwenhoek Hospital
Exclusion criteria
Patients
- that are not mobile or healthy enough to come for an extra visit to the hospital
- having a local recurrence which is not possible to treat anymore, or still planned to be treated
- with lack of basic written and oral command of the Dutch language
- without dental reconstruction at the moment
- with erious psychiatric or cognitive problems that would preclude completion of self-report questionnaires
- living more than 45 minutes distance from the AvL, if it is not possible to combine the visit with a control visit
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
Register | ID |
---|---|
CCMO | NL29853.031.09 |