To study the incidence and prevalence of HIV/AIDS and other bloodborne and sexually transmitted diseases and (HIV) related infections.To study the (natural) course, the (moleculair) epidemiology, pathogenesis and the effect of treatment and other…
ID
Source
Brief title
Condition
- Other condition
Synonym
Health condition
hiv/AIDS, bloedoverdraagbare en seksueel overdraagbare en (hiv) gerelateerde aandoeningen
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
HIV-infection, bloodborne and sexually transmitted diseases and (HIV) related
infections.
(Genetic) markers of HIV-infection, bloodborne and sexually transmitted
diseases and (HIV) related infections.
Secondary outcome
not applicable.
Background summary
Since 1985 the research department of the Municipal Health Service of Amsterdam
focuses on research on HIV/AIDS, bloodborne and sexually transmitted diseases
and (HIV) related infections in drug users. This protocol is admitted to
broaden and replace all preceding protocols on this cohort of drug users
previously approved by the Medical Ethics Board of the AMC and the MHS
Amsterdam.
Study objective
To study the incidence and prevalence of HIV/AIDS and other bloodborne and
sexually transmitted diseases and (HIV) related infections.
To study the (natural) course, the (moleculair) epidemiology, pathogenesis and
the effect of treatment and other interventions in HIV infections and other
bloodborne and sexually transmitted diseases and (HIV) related infections.
The riskfactors, including behaviour, for and spread of bloodborne and sexually
transmitted disesases and HIV and (HIV) related infections.
Immunological and virological markers of bloodborne and sexually transmitted
diseases and HIV and (HIV) related infections.
Genetic background of participants and the relation between genetic markers and
sensitivity to viral infections and clinical course of infections.
Depending on future developments the number of infections studied can be
extended.
Study design
Open, observational cohort study among drug users.
Study burden and risks
Participating in the ACS among drug users does not have any negative
consequential risks for the participants, besides a possible small and
transient bruise after venapuncture.
Once every 6 months questionnaires and blood samples are collected and
depending on the research question physical examination and additional body
tissue samples can be collected.
Nieuwe Achtergracht 100
1018 WT Amsterdam
NL
Nieuwe Achtergracht 100
1018 WT Amsterdam
NL
Listed location countries
Age
Inclusion criteria
drug users, living in the Netherlands, 18 years of age and older, signed Informed Consent, willing to fill out/answer questionnaires, willing to donate blood samples and other body tissue samples. Agreeing to be told results of medical tests.
Exclusion criteria
not relevant: if inclusion criteria are fullfilled, the person can join the ACS
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| CCMO | NL27103.018.09 |