To investigate whether propriocepsis or reflexes are present after nerve reconstruction
ID
Source
Brief title
Condition
- Muscle disorders
- Peripheral neuropathies
Synonym
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
Reflex gain and modulation
Secondary outcome
Muscle force around shoulder and elbow; Range of Motion of shoulder and Elbow
Background summary
Patients with a peripheral nerve lesion who have a paresis of the elbow flexing
muscles, often undergo surgery to reconstruct the damaged nerves. Although the
surgery usulally results in ganing muscle force, functionality is not always
restored. This may be due to the fact that the propriocepsis or the feedback or
the reflexes are not restored.
Study objective
To investigate whether propriocepsis or reflexes are present after nerve
reconstruction
Study design
Using a planar haptic device, force and psoition perturbations are applied to
the hand. The recations of the subject are measured. System identification and
neuromuscular modelling are used to determine the tranfer functions of
perturbation to reaction and subsequently to derive the reflex gain and
modulation. Cross sectional study with 10 patients and 10 age and sexe matched
control subjects
Study burden and risks
The risks are minimal
The burden comprises one session of measurements, taking in total 3 hours, of
which 45 minutes actual measurement time
Postbus 9600
2300 RC Leiden
Nederland
Postbus 9600
2300 RC Leiden
Nederland
Listed location countries
Age
Inclusion criteria
- Patients with brachial plexus lesions or nerves innervating the elbow flexor muscles resulting in a paresis of the elbow flexor muscles;- There is some handfunction left;- Patients underwent primary nerve reconstruction with mesurable feffect, i.e. the muscle strength did increase with at least one point on the MRC scale
Exclusion criteria
- joint contractures in elbow or shoulder
- no return of elbow flexion strength after surgery
- other neurological diseases
Design
Recruitment
Medical products/devices used
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| CCMO | NL27735.058.09 |