The primary objective is to investigate (visual) temporal processing in patients with right parietal cortex damage, in particular temporal ventriloquism. The following assessments will be made:Task 1: visual Temporal Order Judgment (VTOJ) for…
ID
Source
Brief title
Condition
- Other condition
Synonym
Health condition
hersenletsel (agv trauma, pathologie, cva)
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
Task 1: The main parameter in task 1 is the Just Noticeable Difference (JND)
for visual temporal order. The JND reflects the smallest time difference (in
milliseconds) between the two visual stimuli (flashes) that participants need
to perceive for a correct visual temporal order. The JND is calculated for each
group and the two conditions of the task.
Secondary outcome
Task 2: the percentage omissions (total number of omissions divided by total
number of targets) reflects a subject's degree of neglect.
Background summary
The perception of the world around us largely determines how we attend to and
behave in the world. To correctly respond to situations around us, it is
important to receive the right information from our senses about this
situation. Timing plays an important role in this process; if information from
(for example) our eyes and ears are not at approximately the the same time
passed to our brain, it is impossibly to integrate this information into a
coherent percept. Previous research has shown that the right parietal cortex
plays an important role in timing mechanisms with a crucial role for the right
parietal cortex in visual temporal processing. People with right parietal
cortex damage often suffer from neglect, which is mainly characterized in
spatial terms. Results from above mentioned studies suggest also a temporal
role in neglect. In this current project we will follow up on previous findings
by exploring temporal processing in patients with right parietal cortex
lesions, in particular the effects of temporal ventriloquism.
Study objective
The primary objective is to investigate (visual) temporal processing in
patients with right parietal cortex damage, in particular temporal
ventriloquism. The following assessments will be made:
Task 1: visual Temporal Order Judgment (VTOJ) for measuring visual temporal
processing and the effects of temporal ventriloquism
Task 2: Cancellation task for measuring possible neglect
Study design
Task 1: the VTOJ has two conditions, silent control and clicks at an
audiovisual delay of ~100 ms. The visual flashes are presented at 10 SOAs
ranging from -600 ms to +600 ms with steps of 100, 50 and 25 ms. The visual
flashes are presented in both the left and the right visual hemifield at ~10
degrees from fixation. This results in 40 unique trials, each randomly
presented 16 times in five blocks of 128 trials each.
Task 2: the cancellation task consists of 468 letters spread over an A4 paper.
Within the 468 stimuli, 40 targets letters *O* are presented. It is the
subject*s task to cancel out all the *O**s.
Study burden and risks
As far as we can consider there are no risks related to this study. Therefore
we do not foresee any difficulties that could lead to any medical, mental or
physical problems. The tasks are easy to perform, there is no correct or false
answer for the subject and the subject can get a break at any time. Therefore
the mental load is minimalized.
This study is group-related, because it could not be conducted without the
participation of right parietal brain damaged patients (all belonging to one
group). As stated before, we would like to acquire more knowledge on temporal
processing and temporal ventriloquism in persons with right parietal lesions.
Therefore, the inclusion of right parietal patients (and comparable left
hemisphere lesioned persons as a control group) is necessary.
Warandelaan 2
Postbus 90153, 5000 LE Tilburg
NL
Warandelaan 2
Postbus 90153, 5000 LE Tilburg
NL
Listed location countries
Age
Inclusion criteria
Inclusion criteria for the right parietal brain damage subjects:
- Presence of right parietal brain damage, diagnosed by a neurologist based on CT scan(s)
- 18 years or older
- Normal hearing and normal or corrected to normal vision
- Written informed consent;Inclusion criteria for the left hemisphere brain damage subjects:
- Presence of left parietal brain damage, diagnosed by a neurologist based on CT scans (damage should reflect the lesion of a right parietal patient included in the study concerning location and size and patients should have a comparable post-trauma period)
- 18 years or older
- Normal hearing and normal or corrected to normal vision
- Written informed consent
Exclusion criteria
- Evidence of a serious medical, neurological or psychiatric illness (apart from the current brain damage), seizure disorders, trauma or a use of medications affecting the nervous system
- History of brain damage
- Phatic deficits;Individuals in the healthy control group are excluded if there are concerns about:
- psychiatric conditions
- hearing and/or vision disabilities
Design
Recruitment
Followed up by the following (possibly more current) registration
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Other (possibly less up-to-date) registrations in this register
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In other registers
| Register | ID |
|---|---|
| CCMO | NL26989.008.09 |