To asses if the MRI 7 Tesla scanner provides better imaging of the DBS targets and therefore can improve planning for stereotactic surgery.
ID
Source
Brief title
Condition
- Other condition
Synonym
Health condition
bewegingsstoornissen
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
better MR imaging of the DBS targets (STN,VIM,ZI,Gpi and PPN). Study
parameters: signal to noise ratio, resolution, contrast and scantime
Secondary outcome
nvt
Background summary
Stereotactic surgery is a well established treatment in patients with movement
disorders (MD). Its success is highly dependent on the accuracy of the
preoperative target planning, therefore the target(s) have to be clearly
identified. We make a qualitative comparison between the 7 Tesla MRI scanner
in Utrecht and the currently used 1.5 and 3 Tesla MRI scanners in Groningen.
We expect that the Deep Brain Stimulation (DBS) targets on the 7 Tesla MR
images will be more clearly defined. Furthermore we expect that the images will
give information of the position of the Pendunculopontine nucleus, currently
not clearly identifiable from surrounding structures.
This study will assess the future role of the MRI 7 Tesla in Stereotactic
Surgery.
Subjects will undergo three MRI sessions. The total time spent will be around
four hours.
Study objective
To asses if the MRI 7 Tesla scanner provides better imaging of the DBS targets
and therefore can improve planning for stereotactic surgery.
Study design
Qualitative comparison study of DBS targets.
Study burden and risks
There is no risk associated with this purely MRI research.
hanzeplein 1
9700 rb
Nederland
hanzeplein 1
9700 rb
Nederland
Listed location countries
Age
Inclusion criteria
Healthy subjects: - No known illness or disease and passing MRI inclusion criteria.;MD group: - Diagnosed movements disorder and passing inclusion criteria for DBS and MRI.
Exclusion criteria
All
- younger than 18 years of age
- presence of metal objects in the body.
- known brain anomalies
- claustrophobia
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| CCMO | NL25023.042.08 |