To assess the accuracy of the electronic nose in the diagnosis of pulmonary embolism.
ID
Source
Brief title
Condition
- Embolism and thrombosis
Synonym
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
the smell-print provided by the electronic nose.
Secondary outcome
the negative and positive predictive values for the diagnosis of pulmonary
embolism.
Background summary
The differential diagnosis of acute pulmonary thromboembolism remains extensive
and specialized diagnostic procedures are needed to confirm or exclude
diagnosis. Recently, *omics* techniques became available, providing
possibilities for analyzing the overall molecular characteristics of various
biological samples by a single measurement. The electronic nose is a handheld
device including on-board pattern recognition analysis software, providing the
potential option of *on the spot* diagnosis of acute PE.
Study objective
To assess the accuracy of the electronic nose in the diagnosis of pulmonary
embolism.
Study design
prospective cohort study
Study burden and risks
Patients will take the electronic nose test, which includes breathing normally
through a mouthpiece for 5 minutes and then exhaling a vital capacity volume
into a Tedlar bag connected to an expiratory port.
The analysis of the exhaled breathing volume carries no risks for the
patients.
Meibergdreef 9
1105 AZ Amsterdam
Nederland
Meibergdreef 9
1105 AZ Amsterdam
Nederland
Listed location countries
Age
Inclusion criteria
Patients with clinically suspected pulmonary embolism
Exclusion criteria
Age < 18 years
LMWH or unfractionated heparin 24 hrs or more prior to eligibility assessment
vitamin K antagonists (coumarin derivates)
inability to perform the electronis nose test
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| CCMO | NL26237.018.08 |