First objective; to document the existence and to categorize vocal fold pathology after short term intubation and to study voice related patient complaints after short term intubation. Second and third objective; to study the pattern/type of injury…
ID
Source
Brief title
Condition
- Other condition
- Procedural related injuries and complications NEC
Synonym
Health condition
stemklachten
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
Vocal fold pathology documented by videolaryngostroboscopy, voice analysis and
validated questionnaires.
Secondary outcome
not applicable
Background summary
Long-term and crash intubations have adverse effects on the vocal folds. After
short term intubations hoarseness complaints do exist shortly after detubation,
but its effects on the vocal folds are unknown. We aim to investigate the
incidence and severity of vocal fold pathology after short term intubation.
Study objective
First objective; to document the existence and to categorize vocal fold
pathology after short term intubation and to study voice related patient
complaints after short term intubation.
Second and third objective; to study the pattern/type of injury and to identify
possible risk factors. To investigate the relationship between post-operative
hoarseness and findings at videolaryngostroboscopy
Study design
We propose to perform a structured observational study to document the
existence of vocal fold pathology and to categorize vocal fold pathology after
short term intubation and to ask patients about their voice quality after short
term intubation.
Based on the findings of this study, future studies can be designed aimed at
optimizing intubation techniques, devices and material.
Study burden and risks
Participants will be asked to complete the Voice Handicap Index (VHI) pre- and
post-operatively, this takes approximately 10 minutes.
A videolaryngostroboscopy is performed pre- and post-operatively. With a rigid
90 degree endoscope the vocal folds are monitored via the mouth while the
participant is making an [i]-like sound. Seldom a retching feeling occurs
during this test. Vomiting is very rare.
The participants will undergo an acoustic analysis of the voice whereby a
microphone is attached to the head which does not provide any discomfort.
Postbus 5800
6202 AZ
NL
Postbus 5800
6202 AZ
NL
Listed location countries
Age
Inclusion criteria
All adult (>18years) patients, male and female, undergoing an elective procedure under general anaesthesia requiring endotracheal intubation or laryngeal mask ventilation. Short term intubation is defined as lasting less than 3 hours.
Exclusion criteria
Upper airway and neck operations. Procedures after which view on the larynx is disabled. Procedures taking more than 3 hours.
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
In other registers
| Register | ID |
|---|---|
| Other | 2549 |
| CCMO | NL33665.068.10 |
| OMON | NL-OMON27083 |