Evaluation of the CLIP strategy of glaucomatous loss
ID
Source
Brief title
Condition
- Glaucoma and ocular hypertension
Synonym
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
Full-threshold and CLIP: Mean Deviation (MD). The MD is a widely used parameter
that reflect the severity of glaucomatous defects.
Secondary outcome
N/A.
Background summary
The full-threshold (FT), the Swedish Interactive Threshold Algorithm (SITA) and
the supra-threshold (ST) are three well known and most used strategies of the
Humphrey Field Analyzer (HFA) for the detection and follow-up of glaucoma
patients. Less known is the Twinfield Oculus perimeter, which has the same
full- and suprathreshold strategies, and the internally developed Continuous
Light Increment Perimetry (CLIP). The Twinfield perimeter has several
advantages over the HFA and particularly the CLIP strategy, with a short test
time, is a potentially interesting development (unreliable examinations are
correlated with fatigue making short test time essential). However, there is a
shortage of good comparative studies concerning the CLIP strategy.
Study objective
Evaluation of the CLIP strategy of glaucomatous loss
Study design
Sectional comparison between two perimeter strategies: full-threshold vs CLIP.
Study burden and risks
Minimal burden: 2x10, 2x5 and 2x2 minutes (last one concerns supra- threshold
strategy, see study design in research protocol) looking at a screen en pushing
a button when a light spot is seen. The visit is scheduled during a regular
visit to our outpatient clinic.
Applies to glaucoma patients who are already being monitored with threshold
perimetry, therefore, there is no risk involved of unexpected findings (e.g.
detecting disease in a previously healthy individual).
Hanzeplein 1
Postbus 30.001 9700 RB Groningen
NL
Hanzeplein 1
Postbus 30.001 9700 RB Groningen
NL
Listed location countries
Age
Inclusion criteria
Glaucoma patients aged 18 years or older that visit our outpatient clinic for a regular appointment and provide informed consent.
Exclusion criteria
Best corrected Visual Acuity < 0.5 caused by non-glaucomatous pathology
Visual Field Loss caused by non-glaucomatous pathology
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| CCMO | NL32823.042.10 |