The aim of this study is to determine whether the hydration status influences the RNFL thickness.
ID
Source
Brief title
Condition
- Retina, choroid and vitreous haemorrhages and vascular disorders
- Neurological disorders of the eye
Synonym
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
Delta RNFL.
Secondary outcome
n/a
Background summary
The measurement of the retinal nerve fibre layer (RNFL) thickness using OCT is
accurate to 3-5 um. Neurons can be up to 20 um thick. This implies that
potentially OCT allows to detect changes in cellular volume. A natural
situation where changes in cellular volume occur is sport related dehydration.
After sport we feel thirsty and have a drink in order to rehydrate. Here we
want to measure the thickness of the RNFL before and after sport and after
rehydration.
Study objective
The aim of this study is to determine whether the hydration status influences
the RNFL thickness.
Study design
A charity run organised for the sixth time by the VUmc. Twenty runner and 20
bystanders who volunteer to the OCT study will be measured at 3 time-points,
before and after the run as well after having a free sport drink. Standard
statistical techniques will be applied to investigate whether there was a
change in the RNFL thickness.
Study burden and risks
There is no risk associated with the OCT investigation.
De Boelelaan 1117
1081 HV Amsterdam
NL
De Boelelaan 1117
1081 HV Amsterdam
NL
Listed location countries
Age
Inclusion criteria
healthy, age 18-60
Exclusion criteria
any eye disease
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| CCMO | NL33805.029.10 |