To investigate the effects of exposure to low intensity monochromatic blue light compared to the effects of standard light trherapy in the treatment of SAD and winterblues
ID
Source
Brief title
Condition
- Mood disorders and disturbances NEC
Synonym
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
Sores on the SIGH-SAD interviews
Secondary outcome
none
Background summary
Seasonal affective disorder, wintertype, according to DSM-IV is depreesion
with a seasonal pattern in wich the complaints exist in fall/winter and
remission tooks place in spring/summer at an almost yearly
basis.Epidemiological research in the Netherlands shows that 3% of the adults
suffer from SAD and 8% from winterblues..
It has been shown that light treatment is effective, but the etiology of SAD
and the working mechanism of light treatment are still unknown. One of the
hypotheses is the phase shift hypothesis, which postulated that some biological
processes are shifted compared to the 24 h rhythm of the environment. Exposure
to bright light can cause a phase shift. If the biological clock is running in
phase, SAD complaint can improve..
Recently novel photoreceptors in the eye are discovered. They have no
influence on the visual system, but are sensitive for light, especially for
light with a short wavelength (blue light). If blue light with a low intensity
can have the same effect s compared to standard light therapu with a high
intensity, than it is possible to ssimplify the traetment an to incorperate it
in the life style of the
Study objective
To investigate the effects of exposure to low intensity monochromatic blue
light compared to the effects of standard light trherapy in the treatment of
SAD and winterblues
Study design
A treatment stud in which in the experimental condition teh effects of exposure
of low inetnsity blue monochromatic light is compared to the effects of
exposure tot standard light treatment in the treatment of SAD and winterblues
Intervention
Experimental treatment is exposure to low intensity blue monochromatic light,
compared to standard light treatment
Study burden and risks
The risk that the experimental treatment is less effective compared to standard
light treatment. Participants needs 5 minutes a day for filling out small
questionaires an weekly 45-75 minutes for a visit to teh clinic (total 3.5 h)
to participate in an inteview and filling out questionnaires.
P.O. Box 20100
9200 CA Drachten
NL
P.O. Box 20100
9200 CA Drachten
NL
Listed location countries
Age
Inclusion criteria
- age between 18-65 yr
- no other treatments for seasonal complaints during the same time
- no traveling to southern counties during study period
- no use of tanning fixtures during study period
- informed consent;1. seasonal affective disorder (SAD), winter type, according to DSM-IV
score of at least 18 on the first 24 items of the SIGH-SAD
2. sub-syndromal seasonal affective disorder (sub-SAD, winterblues) acording to the Kasper
et al. (1988) criteria:
- SPAQ-GSS score of 8,9 or 10 and at least light seasonal complaints or
- SPAQ-GSS score of 11
score of 12-17 on the first 24 items of the SIGH-SAD
Exclusion criteria
other Axis -I disorders according to DSM-IV
acute suicidal risk
use of pschopharmaca or photosensitsizing drugs
eye diseases or complaints exept aging
diabetes
epilepsy
night shifts
Design
Recruitment
Medical products/devices used
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
In other registers
| Register | ID |
|---|---|
| CCMO | NL33067.042.10 |
| OMON | NL-OMON22649 |