reduction of fluid administration of 30%
ID
Source
Brief title
Condition
- Miscellaneous and site unspecified neoplasms malignant and unspecified
Synonym
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
Reduction of fluid by 30 %
Secondary outcome
ICU stay
number of days of mechanical ventilation
use of diuretics postoperative
measurement of inflammation
Background summary
Large amounts of fluid administration leads to more complications and longer
ICU stay after laparotomy. Use of a device like the Flowtrac/vigileo can reduce
the amounts of fluid in order to reduce complication rate and ICU stay.
Study objective
reduction of fluid administration of 30%
Study design
Two groups of 12 patients will be randomized between standard monitoring or
additive monitoring with flowtrac/Vigileo and pulsed dye densitometrie.
Furthermore a few blood samples will be drawn in order to study the
inflammation effect of HIPEC procedures.
Theoretically also the use of postoperative diuretic use should be reduced
Intervention
Extensive monitoring with flow trac vigileo and pulsed dye densitrometry
blood sampling to measure the inflammation proces
Study burden and risks
a few bloodsamples will be drawn (4 ml)
Koekoekslaan 1
3430 EM Nieuwegein
Nederland
Koekoekslaan 1
3430 EM Nieuwegein
Nederland
Listed location countries
Age
Inclusion criteria
HIPEC procedure
age 18 years and older
Exclusion criteria
cardiac aritmia
LVEF < 40%
severe coronary artery disease
not possible to do an optimal debulking
use of diuretics preoperatively
Design
Recruitment
Medical products/devices used
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| CCMO | NL33966.100.10 |