The objective of the studie is to develop a reliable and discriminative measurment protocol to determine the upper extremity function in boys with DMD. This measurement protocol will be based on 3D movement analysis and surface EMG measurements.
ID
Source
Brief title
Condition
- Muscle disorders
Synonym
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
The primary outcome measures of this study are the kinematics of the elbow and
shoulder, the active range of motion (ROM) of the elbow and shoulder and the
normalized EMG signal.
Secondary outcome
Secundary outcome measures are kinematics of the head and the thorso.
Background summary
When a boy with Duchenne Muscular Dystrophy (DMD) is wheelchair confined, he
becomes completely dependent on his upper extremity function. Despite this,
little research had been done on upper extremity function in boys with DMD. In
addition the measurement instruments for upper extremity function are little
discriminative. Therefore it is very important that a measurement protocol is
developed that is able to determine upper extremity function reliably and
discriminatively. This way the deterioration of upper extremity function can be
evaluated. And eventually a good measurement protocol can be used to evaluate
interventions aimed at the improvement of upper extremity function.
Study objective
The objective of the studie is to develop a reliable and discriminative
measurment protocol to determine the upper extremity function in boys with DMD.
This measurement protocol will be based on 3D movement analysis and surface EMG
measurements.
Study design
The study will be an explorative case-control study, in which subjects perform
the measurement protocol one single time. To do this reflective markers and
EMG-electrodes are placed on the skin and then the subject is asked to perform
some movements of the elbows and shoulders.
Study burden and risks
The burden and risks associated with participation are very small. The
movements that are measured are movements that are also performed in daily
living and the movements will not be forced. Furthermore, the measurement
protocol is not invasive.
Postbus 9101
6500 HB Nijmegen
NL
Postbus 9101
6500 HB Nijmegen
NL
Listed location countries
Age
Inclusion criteria
DNA established diagnosis of DMD
Boys who are at the end of their ambulation or are recently wheelchair confined
Boys that are able to sit for 20 minutes without arm and with back support
Boys who have Brooke scale one or two (able to raise hands above the head)
Exclusion criteria
Other disabling diseases influencing upper extremity mobility
Boys <= ten years old
Surgical scoliosis correction
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| CCMO | NL32552.091.10 |