1. To investigate the associations between DSM-IV personality disorder and attachment style. 2. To investigate whether attachment related anxiety and avoidance, as more fundamental personality features than the DSM-IV personality classification,…
ID
Source
Brief title
Condition
- Personality disorders and disturbances in behaviour
Synonym
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
primary study parameters: score attachment related anxiety and avoidance;
subjective labeling of emotional pictures; heart rate and skin conductance
response to stress; cortisol and oxytocine response to stress.
Secondary outcome
n.v.t.
Background summary
Despite the theoretical centrality of attachment style and affective
functioning in patients with severe personality disorder, there is a scarcity
of studies in which attachment style, subjective experience of affective
functioning and psychophysiological measures are combined to explore
empirically the associations between clinical symptoms and fundamental
psychological functioning.
Study objective
1. To investigate the associations between DSM-IV personality disorder and
attachment style.
2. To investigate whether attachment related anxiety and avoidance, as more
fundamental personality features than the DSM-IV personality classification,
predict subjective labeling and physiological (ANS) responding to emotional
pictures and a standardized psychosocial stress test in female psychotherapy
patients.
3. To investigate whether attachment related anxiety and avoidance are
predictive for the oxytocin and cortisol responses to emotional pictures and a
standardized psychosocial stress test in female psychotherapy patients.
4. To investigate whether female patients with a personality disorder differ
from healthy female controls regarding baseline cortisol and oxytocin levels
and psychophysiological reactions to emotional pictures and to a standardized
psychosocial stress test.
Study design
observational study with noninvasive measures.
Study burden and risks
Duration assessments per subject: clinical/diagnostic assessments during a
session of 1-2.5 hrs embedded in clinical practice; psychophysiological
measurements, including saliva sampling, during a single session of 2 hrs.
Assessments: clinical/diagnostic assessments and questionnaires;
emotional/cognitive task; psychosocial stress task; heart rate, respiration and
skin conductance measures + 9 times sampling of saliva cortisol and oxytocin.
's Gravendijkwal 230
3015 CE Rotterdam
NL
's Gravendijkwal 230
3015 CE Rotterdam
NL
Listed location countries
Age
Inclusion criteria
All female patients in psychotherapeutic treatment at the department of Psychotherapy of the Riagg Rijnmond are invited to participate in the study and to enter the additional diagnostic procedures after full verbal and written informed consent.
Selection of controls: based on medical history information and present state physical and mental condition (established by the intake-interview and questionnaire), the subjects must be in good health, and without a history of psychiatric illness. The control subjects must be drug-free at the time of the study.
Exclusion criteria
Patients with a history of schizophrenia or bipolar disorder, current substance or alcohol abuse, or the use of cortisone or psychotropic medication will be excluded from the study. Also, patients who are visual disabled, with neurological, cardiovascular or respiratory diseases and those who do not sufficiently master the Dutch language or who have clinically relevant low IQ will be excluded.
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| CCMO | NL32516.078.10 |