The aim of the current study is to identify couplings of muscle activation patterns (muscle synergies) in reaching movements in stroke patients. Insight in the motor control of stroke patients can contribute to improve the disabled arm functioning…
ID
Source
Brief title
Condition
- Central nervous system vascular disorders
Synonym
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
In the current study, patterns of muscle activity (measured with
electromyography (EMG)) and kinematics (measured with an instrumented
exoskeleton) during reaching movements in non-affected persons and stroke
patients are considered. Muscle synergies will be extracted from the recorded
EMG data, with accompanying time onset and amplitude parameters. We are
interested in the difference in amount of synergies between both groups, the
muscles included in the synergies and the accompanying parameters.
Secondary outcome
Apart from the primary outcome, the relation between motor functioning
(measured with the Fugl-Meyer test and kinematics) and extracted synergies will
be considered in the stroke population.
Background summary
Many stroke patients suffer from changes in motor function. Underlying
mechanisms of this changed motor function are not known yet. Muscle activation
patterns, responsible for the production of movements, have to be studied to
get insight in motor control. Couplings of muscle activation patterns (muscle
synergies) have been extracted from muscle activation patterns in non-affected
persons. To gain insight in motor control in stroke patients, muscle synergies
also have to be studied in this population. Comparing the presence of
synergies in stroke patients with non-affected persons and relating these
findings with the presented motor behavior will provide insight in the role of
muscle synergies in the production of changed motor behavior in stroke
patients. Rehabilitation is of importance to promote arm function in order to
perform activities of daily living. Insight in motor control of stroke patients
can help improving rehabilitation programs.
Study objective
The aim of the current study is to identify couplings of muscle activation
patterns (muscle synergies) in reaching movements in stroke patients. Insight
in the motor control of stroke patients can contribute to improve the disabled
arm functioning by improving rehabilitation therapy.
Study design
The study has a cross-sectional design. Muscle activation patterns and
kinematics of the arm and shoulder will be measured during different conditions
of a reaching task, performed at different velocities, in one measurement
session. No intervention will be applied.
Study burden and risks
The risks for the subjects are limited to a minimum, since the movement tasks
represent functional and familiar arm movements and are performed only within
the scope of the subject*s ability while he/she is seated. In addition, the
measurements used in this study (EMG, motion analysis, functional scales) are
all noninvasive and involve no risks to the participants in any way.
Participation of a subject in this experiment has no direct benefit for
him/her, other than expanding knowledge about underlying mechanisms relevant
during the restoration of arm function during post-stroke rehabilitation. This
may eventually aid in the development of new applications or adaptations to
existing treatments in the rehabilitation of arm function after stroke.
Roessingsbleekweg 33b
7522 AH Enschede
NL
Roessingsbleekweg 33b
7522 AH Enschede
NL
Listed location countries
Age
Inclusion criteria
- At least 6 months post-stroke.
- The function of the right arm is affected.
- Able to lift the right arm against gravity and perform a horizontal and vertical reaching movement.
- Able to decide whether to participate or not and to sign an informed consent.
Exclusion criteria
- Pain in the upper extremity or shoulder, either in rest or during movements.
- Orthopedic or rheumatologic ailments, which might constrain the mobility and/or force of the arm.
- Additional neurological diseases.
- Inability to understand and/or to follow the instructions given.
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| CCMO | NL30813.044.09 |