Assess the natural course of UNE in patients with mild to moderate symptoms by using clinical, electrophysiological and ultrasonographic data
ID
Source
Brief title
Condition
- Peripheral neuropathies
Synonym
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
Differences over time in the results of electrodiagnostic and sonographic
studies
Secondary outcome
Not applicable
Background summary
Ulnar neuropathy at the elbow (UNE) is considered the second most common
entrapment neuropathy. Diagnosis of UNE is made on clinical and
electrophysiological examination. Ultrasound of the ulnar nerve is becoming
more available and has been validated in recent years. There is no gold
standard in the treatment of UNE.
It is well known that mild to moderate cases of UNE, i.e. with solely sensory
symptoms and sensory plus mild motor symptoms respectively, improve over time
with lifestyle changes. Though abovementioned techniques have established their
part in diagnosing UNE, no prospective study yet focused on possible short-term
changes and differences in electrophysiologic and ultrasonographic studies to
monitor the disease or decision making regarding treatment.
Study objective
Assess the natural course of UNE in patients with mild to moderate symptoms by
using clinical, electrophysiological and ultrasonographic data
Study design
Prospective cohort study
Study burden and risks
The first ultrasound and the second visit with all three examinations is the
extra burden for the patients. This extra burden mainly applies to those
patients with improvement of their complaints, since in clinical practice most
patients will receive a second EMG and/or additional ultrasonographic
examination with deterioration of their symptoms.
Leyweg 275
2545 CH Den Haag
NL
Leyweg 275
2545 CH Den Haag
NL
Listed location countries
Age
Inclusion criteria
Clinically suspect ulnar neuropathy at the elbow
Exclusion criteria
Anatomical abnormalities near the elbow, including mass lesions and acute penetrating traumatic lesions
Previous ulnar nerve or elbow surgery
Pregnancy
Paresis of ulnar-innervated intrinsic hand muscles on the Medical Research Council (MRC) scale of 3 or lower
Being unable to understand or read the Dutch language
Design
Recruitment
metc-ldd@lumc.nl
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
Register | ID |
---|---|
CCMO | NL31928.098.10 |