To evaluate if a low-carbohydrate diet leeds to less physiological FDG-uptake in the myocard. Patients on a low-carbohydrate diet will be compared to patients without such a diet.
ID
Source
Brief title
Condition
- Miscellaneous and site unspecified neoplasms malignant and unspecified
Synonym
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
Kwantitative evaluation of FDG-uptake in the myocard.
Secondary outcome
Semi-kwantitative evaluation of FDG-uptake in the myocard.
Evaluation of the relevence of the FDG-uptake in the myocard for te evaluation
of the FDG-PET-scan.
Evaluation of the patients experience with regard to the burden of the diet.
Background summary
Some patients have FDG-uptake in the myocard. This physiological uptake can be
disadvantageous for evaluation of abnormalities in mediastinum or lung tissue.
These disadvantageous effects can also appear distal of the myocard, probably
caused by competition for the FDG. By giving patients a low-carbohydrate diet
at least 24 hours before the start of the PET-scan, the aim of this pilot is to
decrease the FDG-uptake in the myocard. With the results of the pilot a trial
can be designed to investigate the usefulness of the diet for the evaluation of
PET-scans in different patient categories.
Study objective
To evaluate if a low-carbohydrate diet leeds to less physiological FDG-uptake
in the myocard. Patients on a low-carbohydrate diet will be compared to
patients without such a diet.
Study design
Pilot, prospective, randomized, single-center, single-blind, parallel,
interventional.
Intervention
Low-carbohydrate diet at least 24 hours before the PET-scan.
Study burden and risks
There are no risks. The extra burden consists of: filling in forms (dietform,
questionnaire and medication list) and complying to a low-carbohydrate diet for
at least 24 hours.
Heidelberglaan 100
3584 CX UTRECHT
Nederland
Heidelberglaan 100
3584 CX UTRECHT
Nederland
Listed location countries
Age
Inclusion criteria
18 years and over
outpatients
oncological patients
Exclusion criteria
younger then 18 years
diabetes mellitus
sarcoidosis
On a low-carbohydrate diet <4 weeks before PET-scan
Incompetent patients
Clinical patients
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| CCMO | NL30478.041.09 |