The primary goal of the study is to investigate whether additional intensive strength training can lead to increases in strength and voluntary activation and pysical functioning before surgery. Further, it is a goal to study if there are indications…
ID
Source
Brief title
Condition
- Joint disorders
Synonym
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
Knee extension force of both legs
voluntary activation of the quadriceps (with use of electro stimulation)
Secondary outcome
Cross sectional area of the quadriceps
Time for the *five times sit to stand test
Distance walked during the *six minute walk test*
Time for the stair climb test
Range of motion of the knee
Time for a balance test
WOMAC
VAS pain
Background summary
95% of the patients undergoing total knee arthroplasty are diagnosed with
osteoarthritis. Osteoarthritis is a joint disease which is characterized by
pain, loss of force and problems during activities of daily life. This can
result in reduced social participation and quality of life. Current advice on
preoperative training is very diverse. Some hospitals advise patient to consult
a physiotherapist before surgery, while others do not. Between physiotherapists
there are large differences in treatment. While some only train walking with
aids, others perform intensive strength training. Because there is evidence
that intensive strength training is beneficial post surgery, our hypothesis is
that preoperative training also leads to increases in muscle strength,
voluntary activation, and physical functioning. Further we expect to find
indications that positive preoperative effects promote postoperative recovery.
This study can help to shorten recovery and increase the quality of life for
patients undergoing total knee arthroplasty.
Study objective
The primary goal of the study is to investigate whether additional intensive
strength training can lead to increases in strength and voluntary activation
and pysical functioning before surgery. Further, it is a goal to study if there
are indications that preoperative strength, activation and functioning are
related to recovery post surgery.
Study design
Randomized clinical trial
Intervention
The intervention will be a six week intensive strength training program pre
surgery. The training will be performed twice a week. See the protocol for
further details.
Study burden and risks
Subjects will participate in research project executing a 6 week strength
training program training 2 days/week. Measurements will be performed at 4
different time slots including tests that assess neuromuscular function and
functional tasks (duration about 1.5 hours). Subject may experience some
discomfort during electrical stimulation and/or muscle soreness after muscle
tests. Furthermore, the risks during training and testing sessions are
relatively low because of thorough screening prior to participation, use of
skilled and licensed therapists and safety precautions throughout training and
testing. The expected beneficial training effects in combination with the
limited risks would justify execution of the proposed study.
Van der Boechorststraat 9
1081 BT Amsterdam
NL
Van der Boechorststraat 9
1081 BT Amsterdam
NL
Listed location countries
Age
Inclusion criteria
Awaiting unilateral total knee arthroplasty
Age>55
Exclusion criteria
contraindications for training the lower limbs
ASA>2 (American Society of Anesthesiologists)
severe cognitive and/or communicative problems, preventing ability to follow verbal instructions
other problems that would limit the ability to perform the requested tasks
contra-indications for electrical stimulation (unstable epilepsy, cancer, skin abnormalities, pacemaker).
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| CCMO | NL30715.029.10 |