The purpose of the study is to assess the effect of a rinsing or drinking water on the MBB in periodontally and systemically healthy subjects.
ID
Source
Brief title
Condition
- Other condition
Synonym
Health condition
Morning Bad Breath (MBB)
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
Primary outcome variable is the MBB, measured by three devises.
- Oral Chroma©
- Halimeter®
- Organoleptische score: 0-5 scale (Rosenberg et al. 1991a, Rosenberg et al.
1991b further modiefied by Greenman et al. 2004)
Secondary outcome
Secondary outcome variable is:
- Tongue coating (Mantilla et al.)
- Questionnaire about their experience of their MBB and used their regime
Background summary
Halitosis is a general term used to describe an unpleasant or offensive odor
emanating from the oral cavity. Several (non-oral) pathological conditions have
been related to oral malodor, including infection of the upper and lower
respiratory tracts, the gastrointestinal tract, and some metabolic diseases
involving the kidneys or the liver (Manolis 1983). However, clinical surveys
have shown that around 90% of all bad breath odors originate in the mouth
(Delanghe et al. 1997).
To reduce the Morning Bad Breath (MBB) several websites suggest that rinsing or
drinking water upon awakening is effective. Since MBB can be caused by a dry
mouth. Water drinking help to stimulate the saliva production and saturate the
whole mouth. Rinsing seems like the obvious first-aid measure to take (consumer
websites). This home-remedy is however not supported with scientific evidence
Study objective
The purpose of the study is to assess the effect of a rinsing or drinking water
on the MBB in periodontally and systemically healthy subjects.
Study design
Prospective single examiner- blind randomized two-arm parallel design
Intervention
Drinking water 200 milliliter
Study burden and risks
There is no risk
Gustav Mahlerlaan 3004
1081 LA Amsterdam
NL
Gustav Mahlerlaan 3004
1081 LA Amsterdam
NL
Listed location countries
Age
Inclusion criteria
* * 18 years, *Systemic healthy, assessed by medical questionnaires * Non smokers
* No orthodontic appliances * No removable (partial) dentures * Minimum 20 teeth * No caries
* Willing and able to give a written informed consent * Willing to adapted the style rule for 48 hours
Exclusion criteria
* Any pathological alterations of the oral mucosa/ pregnancy * Participation in a clinical study within the previous 30 days * Acute sinusitis or severe oral- pharyngeal infections * On medications which can cause malodor * Reduced salivary flow due to pathological reasons (e.g. Sjögren syndrome) * Subjects unwilling to abstain from additional oral hygiene (only tooth brushing allowed) particularly mouthrinse, chewing gums, flossing, peppermint containing product etc. and alcohol 12 hours prior the first measurement at the study site and until the completion of all measurements
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
In other registers
| Register | ID |
|---|---|
| CCMO | NL38260.018.11 |
| OMON | NL-OMON28921 |