The aim of this study is to assess the number of supragastric belches and reflux episodes before and after speech therapy in GERD patients with troublesome belching symptoms due to an increased number of supragastric belches.
ID
Source
Brief title
Condition
- Gastrointestinal motility and defaecation conditions
Synonym
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
The number of supragastric belches before and after treatment
The number of liquid reflux episodes
Secondary outcome
Symptoms as assessed by questionnaires
Background summary
The majority of belches originates from the stomach. However, in some patients
the eructated air does not originate from the stomach but is sucked or injected
in the esophagus from the pharynx and expelled immediately afterwards in oral
direction again. This behavior is called supragastric belching because the air
does not originate from the stomach and does not reach the stomach either1.
Recently, Hemmink et al demonstrated that supragastric belches can precede
gastroesophageal reflux episodes and these authors suggested that supragastric
belches could elicit reflux episodes2.
Patients with severe and excessive belching as a main symptom are characterized
by an increased frequency of supragastric belches. A recent study performed in
our center demonstrated that supragastric belches are also associated with
troublesome belching in GERD patients. Speech therapy can decrease severity of
belching symptoms in patients with excessive supragastric belching. In GERD
patients with a demonstrated increased frequency of supragastric belches, there
is currently no evidence based treatment available. Speech therapy can
potentially be helpful and is therefore the only therapeutic option available
in this subgroup of GERD patients.
We hypothesize that speech therapy reduces troublesome belching symptoms in
GERD patients by reducing the number of supragastric belches. Furthermore, we
hypothesize that a reduction in supragastric belches also reduces the number of
reflux episodes.
Study objective
The aim of this study is to assess the number of supragastric belches and
reflux episodes before and after speech therapy in GERD patients with
troublesome belching symptoms due to an increased number of supragastric
belches.
Study design
A prospective study using impedance measurements.
Study burden and risks
Patient will undergo an ambulatory imepdance measurement. This is free of risk.
Meibergdreef 9
1105 AZ Amsterdam
NL
Meibergdreef 9
1105 AZ Amsterdam
NL
Listed location countries
Age
Inclusion criteria
>10 supragastric belches preceding reflux episodes (<1s)
Exclusion criteria
Severe motility disorders of the esophagus
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
Register | ID |
---|---|
CCMO | NL37631.018.11 |