Our longstanding goal is to assess the clinical applicability and technical feasibility of EIT in mechanically ventilated critically ill patients with acute lung injury. Our aim is to establish changes in regional lung aeration with EIT during…
ID
Source
Brief title
Condition
- Lower respiratory tract disorders (excl obstruction and infection)
Synonym
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
The main study endpoint is the regional lung aeration, assessed by EIT.
Secondary outcome
-
Background summary
Mechanical ventilation is a life-saving strategy in patients with respiratory
failure. Nevertheless, mechanical ventilation has the potential to aggravate or
even initiate lung injury, causing overdistention of the non-dependent lung
regions and repetitive collapse and re-expansion of dependent lung regions. In
the intensive care arena many different mechanical ventilation strategies are
employed in patients with acute lung injury, in an effort to attenuate this so-
called ventilator-associated lung injury.
Electrical Impedance tomography (EIT) can assess and image changes in regional
lung aeration at the bedside during a ventilation strategy change. This may
make individualized management of mechanical ventilation possible in a safe,
radiation-free manner.
Study objective
Our longstanding goal is to assess the clinical applicability and technical
feasibility of EIT in mechanically ventilated critically ill patients with
acute lung injury. Our aim is to establish changes in regional lung aeration
with EIT during changes in intubated and mechanical ventilated critically ill
patients.
Study design
Observational study.
Study burden and risks
In this observational study there are no risks involved for participating
patients. Patient burden is minimal to none, and comprises of painless
placement of an electrical impedance belt around the lower thorax.
Meibergdreef 9
1105 AZ Amsterdam
NL
Meibergdreef 9
1105 AZ Amsterdam
NL
Listed location countries
Age
Inclusion criteria
- Intubation and mechanical ventilation
- Acute lung injury (acute onset, bilateral infiltrates on CXR, PaO2/FiO2<300mmHg and no clinical signs of left atrial hypertension)
Exclusion criteria
- Age < 18 years
- Presence of a pacemaker
- Presence of an automatic cardiac defibrillator
- Presence of any implantable pumps
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| CCMO | NL38496.018.11 |