To evaluate whether straylight assessments [log(s)] can contribute to develop/refine the decision tree for the indications AC-PIOL, RLE or CE.
ID
Source
Brief title
Condition
- Vision disorders
Synonym
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
Straylight parameter s (logs[s])
Corrected distance visual acuity (CDVA), monocular and binocular
Contrast sensitivity
Secondary outcome
Optical characteristics of the eye.
Outcome of questionnaires.
Background summary
Various means for the correction of refractive errors, including surgical
procedures, are available nowadays. In the absence of early cataract, phakic
intraocular lens (PIOL) implant is one of the suited procedures, whereas in the
presence of early cataract, refractive lens exchange (RLE) is suited. The
absence or presence of early cataract is assessed by ophthalmologists using
slitlamp examination and classical parameters of visual function (visual acuity
[VA] and contrast sensitivity [CS]). However, subclinical lens opacities may
not be identified by slitlamp examination. Although these subclinical opacities
may already cause a functional effect, it may not yet affect VA and CS tests.
However, it may already affect the straylight parameter. In the presence of
early cataract there may be a discrepancy between ophthalmologist's assessment
of the degree of cataract and the patient*s subjective complaints (e.g.
functionally insignificant versus significant cataract). The main cause for
such a discrepancy is glare caused by forward light scatter (i.e. straylight).
Improvement of visual function after refractive correction may, in part, be due
to a reduction of straylight after replacement of the lens, together with its
opacities. It is expected that straylight measurement can be used to
distinguish the relative contribution of refractive error and glare to visual
function impairment.
Study objective
To evaluate whether straylight assessments [log(s)] can contribute to
develop/refine the decision tree for the indications AC-PIOL, RLE or CE.
Study design
Prospective observational case series (pre-post design)
Study burden and risks
Participants do not benefit. Risks are negligible. Patients will be subjected
to study-related measurements twice (i.e. pre- and postoperatively).
Measurements will be performed at the time of regular visits to Focus
Clinic/The Rotterdam Eye Hospital. For the straylight measurements pupils will
be dilated by eyedrops. On average, the extra time required will be 1 hour
every visit.
Schiedamse Vest 180
3011 BH Rotterdam
NL
Schiedamse Vest 180
3011 BH Rotterdam
NL
Listed location countries
Age
Inclusion criteria
Age > 18 years
Informed consent
Bilateral refractive treatment
Exclusion criteria
Ocular pathology other than lens opacities (e.g. cornea opacities,)
Per- or postoperative complications
Posterior capsule opacification
Linguistic barrier
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
Register | ID |
---|---|
CCMO | NL36666.078.11 |